diff --git a/PanACoTA/annotate_module/annotation_functions.py b/PanACoTA/annotate_module/annotation_functions.py
index 1750a723edff9182a83719f7e44696bf0b151e20..bdf47ee2a15ae863273ab70fd452821468e5d1f3 100755
--- a/PanACoTA/annotate_module/annotation_functions.py
+++ b/PanACoTA/annotate_module/annotation_functions.py
@@ -1,6 +1,38 @@
 #!/usr/bin/env python3
 # coding: utf-8
 
+# ###############################################################################
+# This file is part of PanACOTA.                                                #
+#                                                                               #
+# Authors: Amandine Perrin                                                      #
+# Copyright © 2018-2020 Institut Pasteur (Paris).                               #
+# See the COPYRIGHT file for details.                                           #
+#                                                                               #
+# PanACOTA is a software providing tools for large scale bacterial comparative  #
+# genomics. From a set of complete and/or draft genomes, you can:               #
+#    -  Do a quality control of your strains, to eliminate poor quality         #
+# genomes, which would not give any information for the comparative study       #
+#    -  Uniformly annotate all genomes                                          #
+#    -  Do a Pan-genome                                                         #
+#    -  Do a Core or Persistent genome                                          #
+#    -  Align all Core/Persistent families                                      #
+#    -  Infer a phylogenetic tree from the Core/Persistent families             #
+#                                                                               #
+# PanACOTA is free software: you can redistribute it and/or modify it under the #
+# terms of the Affero GNU General Public License as published by the Free       #
+# Software Foundation, either version 3 of the License, or (at your option)     #
+# any later version.                                                            #
+#                                                                               #
+# PanACOTA is distributed in the hope that it will be useful, but WITHOUT ANY   #
+# WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS     #
+# FOR A PARTICULAR PURPOSE. See the Affero GNU General Public License           #
+# for more details.                                                             #
+#                                                                               #
+# You should have received a copy of the Affero GNU General Public License      #
+# along with PanACOTA (COPYING file).                                           #
+# If not, see <https://www.gnu.org/licenses/>.                                  #
+# ###############################################################################
+
 """
 Functions to deal with prokka or prodigal only, according to user request
 
diff --git a/PanACoTA/annotate_module/format_prodigal.py b/PanACoTA/annotate_module/format_prodigal.py
index 89066cbd03665c4644f502af8f876e572fd78b83..1981d11c6dec15106bc31d9be4ef089d211b0a26 100644
--- a/PanACoTA/annotate_module/format_prodigal.py
+++ b/PanACoTA/annotate_module/format_prodigal.py
@@ -1,6 +1,38 @@
 #!/usr/bin/env python3
 # coding: utf-8
 
+# ###############################################################################
+# This file is part of PanACOTA.                                                #
+#                                                                               #
+# Authors: Amandine Perrin                                                      #
+# Copyright © 2018-2020 Institut Pasteur (Paris).                               #
+# See the COPYRIGHT file for details.                                           #
+#                                                                               #
+# PanACOTA is a software providing tools for large scale bacterial comparative  #
+# genomics. From a set of complete and/or draft genomes, you can:               #
+#    -  Do a quality control of your strains, to eliminate poor quality         #
+# genomes, which would not give any information for the comparative study       #
+#    -  Uniformly annotate all genomes                                          #
+#    -  Do a Pan-genome                                                         #
+#    -  Do a Core or Persistent genome                                          #
+#    -  Align all Core/Persistent families                                      #
+#    -  Infer a phylogenetic tree from the Core/Persistent families             #
+#                                                                               #
+# PanACOTA is free software: you can redistribute it and/or modify it under the #
+# terms of the Affero GNU General Public License as published by the Free       #
+# Software Foundation, either version 3 of the License, or (at your option)     #
+# any later version.                                                            #
+#                                                                               #
+# PanACOTA is distributed in the hope that it will be useful, but WITHOUT ANY   #
+# WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS     #
+# FOR A PARTICULAR PURPOSE. See the Affero GNU General Public License           #
+# for more details.                                                             #
+#                                                                               #
+# You should have received a copy of the Affero GNU General Public License      #
+# along with PanACOTA (COPYING file).                                           #
+# If not, see <https://www.gnu.org/licenses/>.                                  #
+# ###############################################################################
+
 """
 Functions to convert prodigal result files to gembase format.
 
diff --git a/PanACoTA/annotate_module/format_prokka.py b/PanACoTA/annotate_module/format_prokka.py
index 0f82d936d6575b17b84048faa6fe2c0b9d7cf9e0..3824e3dedd582e613cc6d7fb0907fa23473774a9 100644
--- a/PanACoTA/annotate_module/format_prokka.py
+++ b/PanACoTA/annotate_module/format_prokka.py
@@ -1,6 +1,38 @@
 #!/usr/bin/env python3
 # coding: utf-8
 
+# ###############################################################################
+# This file is part of PanACOTA.                                                #
+#                                                                               #
+# Authors: Amandine Perrin                                                      #
+# Copyright © 2018-2020 Institut Pasteur (Paris).                               #
+# See the COPYRIGHT file for details.                                           #
+#                                                                               #
+# PanACOTA is a software providing tools for large scale bacterial comparative  #
+# genomics. From a set of complete and/or draft genomes, you can:               #
+#    -  Do a quality control of your strains, to eliminate poor quality         #
+# genomes, which would not give any information for the comparative study       #
+#    -  Uniformly annotate all genomes                                          #
+#    -  Do a Pan-genome                                                         #
+#    -  Do a Core or Persistent genome                                          #
+#    -  Align all Core/Persistent families                                      #
+#    -  Infer a phylogenetic tree from the Core/Persistent families             #
+#                                                                               #
+# PanACOTA is free software: you can redistribute it and/or modify it under the #
+# terms of the Affero GNU General Public License as published by the Free       #
+# Software Foundation, either version 3 of the License, or (at your option)     #
+# any later version.                                                            #
+#                                                                               #
+# PanACOTA is distributed in the hope that it will be useful, but WITHOUT ANY   #
+# WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS     #
+# FOR A PARTICULAR PURPOSE. See the Affero GNU General Public License           #
+# for more details.                                                             #
+#                                                                               #
+# You should have received a copy of the Affero GNU General Public License      #
+# along with PanACOTA (COPYING file).                                           #
+# If not, see <https://www.gnu.org/licenses/>.                                  #
+# ###############################################################################
+
 """
 Functions to:
 
diff --git a/PanACoTA/annotate_module/general_format_functions.py b/PanACoTA/annotate_module/general_format_functions.py
index 023e66ff558720f24cc3fe0d6d98ea0850568208..a1643d0691af5c0c8c1ea1bbfe3719cb8cd3e715 100644
--- a/PanACoTA/annotate_module/general_format_functions.py
+++ b/PanACoTA/annotate_module/general_format_functions.py
@@ -1,6 +1,38 @@
 #!/usr/bin/env python3
 # coding: utf-8
 
+# ###############################################################################
+# This file is part of PanACOTA.                                                #
+#                                                                               #
+# Authors: Amandine Perrin                                                      #
+# Copyright © 2018-2020 Institut Pasteur (Paris).                               #
+# See the COPYRIGHT file for details.                                           #
+#                                                                               #
+# PanACOTA is a software providing tools for large scale bacterial comparative  #
+# genomics. From a set of complete and/or draft genomes, you can:               #
+#    -  Do a quality control of your strains, to eliminate poor quality         #
+# genomes, which would not give any information for the comparative study       #
+#    -  Uniformly annotate all genomes                                          #
+#    -  Do a Pan-genome                                                         #
+#    -  Do a Core or Persistent genome                                          #
+#    -  Align all Core/Persistent families                                      #
+#    -  Infer a phylogenetic tree from the Core/Persistent families             #
+#                                                                               #
+# PanACOTA is free software: you can redistribute it and/or modify it under the #
+# terms of the Affero GNU General Public License as published by the Free       #
+# Software Foundation, either version 3 of the License, or (at your option)     #
+# any later version.                                                            #
+#                                                                               #
+# PanACOTA is distributed in the hope that it will be useful, but WITHOUT ANY   #
+# WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS     #
+# FOR A PARTICULAR PURPOSE. See the Affero GNU General Public License           #
+# for more details.                                                             #
+#                                                                               #
+# You should have received a copy of the Affero GNU General Public License      #
+# along with PanACOTA (COPYING file).                                           #
+# If not, see <https://www.gnu.org/licenses/>.                                  #
+# ###############################################################################
+
 """
 Functions to convert prokka or prodigal results to gembase format:
 
diff --git a/PanACoTA/annotate_module/genome_seq_functions.py b/PanACoTA/annotate_module/genome_seq_functions.py
index 509d8d998656d06320d119d6cad61ab238e7bb74..639a4f9f0c31e6ed5c956d0bebaa70212491631b 100755
--- a/PanACoTA/annotate_module/genome_seq_functions.py
+++ b/PanACoTA/annotate_module/genome_seq_functions.py
@@ -1,6 +1,38 @@
 #!/usr/bin/env python3
 # coding: utf-8
 
+# ###############################################################################
+# This file is part of PanACOTA.                                                #
+#                                                                               #
+# Authors: Amandine Perrin                                                      #
+# Copyright © 2018-2020 Institut Pasteur (Paris).                               #
+# See the COPYRIGHT file for details.                                           #
+#                                                                               #
+# PanACOTA is a software providing tools for large scale bacterial comparative  #
+# genomics. From a set of complete and/or draft genomes, you can:               #
+#    -  Do a quality control of your strains, to eliminate poor quality         #
+# genomes, which would not give any information for the comparative study       #
+#    -  Uniformly annotate all genomes                                          #
+#    -  Do a Pan-genome                                                         #
+#    -  Do a Core or Persistent genome                                          #
+#    -  Align all Core/Persistent families                                      #
+#    -  Infer a phylogenetic tree from the Core/Persistent families             #
+#                                                                               #
+# PanACOTA is free software: you can redistribute it and/or modify it under the #
+# terms of the Affero GNU General Public License as published by the Free       #
+# Software Foundation, either version 3 of the License, or (at your option)     #
+# any later version.                                                            #
+#                                                                               #
+# PanACOTA is distributed in the hope that it will be useful, but WITHOUT ANY   #
+# WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS     #
+# FOR A PARTICULAR PURPOSE. See the Affero GNU General Public License           #
+# for more details.                                                             #
+#                                                                               #
+# You should have received a copy of the Affero GNU General Public License      #
+# along with PanACOTA (COPYING file).                                           #
+# If not, see <https://www.gnu.org/licenses/>.                                  #
+# ###############################################################################
+
 """
 Functions to: