diff --git a/README.md b/README.md
index f76aaeef574b06f938973d4c9cd0a18f96cd0f70..44344019be861af7a3d9a0f764ee6f2584abc637 100644
--- a/README.md
+++ b/README.md
@@ -25,6 +25,10 @@ The analysis is divided in two jupyter notebooks:
 * EcoWG1_library_performance.ipynb
 > In this notebook we analyse the results of a screen performed with the EcoWG1 library and compare its performance to published data.
 
+In addition a script is provided to generate novel libraries following the design rules described in the manuscript.
+Usage:
+
+> python generate_library.py --ref path_to_genbank_file --n number_guide_per_gene --output output_file 
 
 # Live Notebook