diff --git a/README.md b/README.md index 02908a9a2220c5e9588a62f491633c1e9e73120b..4a84c0c79b45608f12abc7e1d7fe6222444f7ddc 100644 --- a/README.md +++ b/README.md @@ -10,12 +10,10 @@ The pipeline is basically written in perl. ## How does it work? It requires an important number of pre-computed datasets: - A Core Genome built with 3 clades and its Phylogenetic reconstruction: - - The clade of interest - - Two clades, outgroups of the clade of interest. + - The clade of interest (Query) + - Two clades, outgroups of the clade of interest (Close and Distant). -Each core-gene alignment has to be divided by clade, so we can distinguish between the clade of interest and the outgroups. *The core genes for the three clades must be formated as HMMer database* - -- The Multiple sequence alignments of each Core-Gene +- Each core-gene alignment has to be divided by clade, so we can distinguish between the clade of interest and the outgroups. *The core genes for the three clades must be formated as HMMer database* - A list of reference sequences - A folder with the metagenomic datasets