diff --git a/README.md b/README.md index b6544e0de782c397ab19162641e2e05b0d2ef34f..02908a9a2220c5e9588a62f491633c1e9e73120b 100644 --- a/README.md +++ b/README.md @@ -9,11 +9,11 @@ The pipeline is basically written in perl. ## How does it work? It requires an important number of pre-computed datasets: -- A Core Genome and its Phylogenetic reconstructions for: - - The Phylogenetic clade of interest - - Two phylogenetic clades, outgroups of the clade of interest. +- A Core Genome built with 3 clades and its Phylogenetic reconstruction: + - The clade of interest + - Two clades, outgroups of the clade of interest. -*The core genomes for the three clades must be formated as HMMer database* +Each core-gene alignment has to be divided by clade, so we can distinguish between the clade of interest and the outgroups. *The core genes for the three clades must be formated as HMMer database* - The Multiple sequence alignments of each Core-Gene - A list of reference sequences