diff --git a/README.md b/README.md index 0c8b768edf053d99f45b79ac928b0ea013eef082..81acca1e84f3ead71529c85c32ee60acc8e4d405 100644 --- a/README.md +++ b/README.md @@ -14,7 +14,7 @@ ePeak is a snakemake-based workflow for the analysis of ChIP-seq data from raw FASTQ files to differential analysis of transcription factor binding or histone modification marking. It streamlines critical steps like the quality assessment of the immunoprecipitation using the cross correlation and the replicate comparison for both narrow and broad peaks. 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xmlns:inkscape="http://www.inkscape.org/namespaces/inkscape" + width="887pt" + height="980pt" + viewBox="0.00 0.00 887.00 980.00" + version="1.1" + id="svg462" + sodipodi:docname="rulegraph_seacr_IA.svg" + inkscape:version="0.92.5 (2060ec1f9f, 2020-04-08)"> + <metadata + id="metadata468"> + <rdf:RDF> + <cc:Work + rdf:about=""> + <dc:format>image/svg+xml</dc:format> + <dc:type + rdf:resource="http://purl.org/dc/dcmitype/StillImage" /> + </cc:Work> + </rdf:RDF> + </metadata> + <defs + id="defs466" /> + <sodipodi:namedview + pagecolor="#ffffff" + bordercolor="#666666" + borderopacity="1" + objecttolerance="10" + gridtolerance="10" + guidetolerance="10" + inkscape:pageopacity="0" + inkscape:pageshadow="2" + inkscape:window-width="3696" + inkscape:window-height="2032" + id="namedview464" + showgrid="false" + inkscape:zoom="2.8897959" + inkscape:cx="864.92143" + inkscape:cy="755.30054" + inkscape:window-x="144" + inkscape:window-y="54" + inkscape:window-maximized="1" + 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188,-468" + id="path57" /> + <text + text-anchor="middle" + x="155" + y="-447.5" + font-family="sans" + font-size="10.00" + id="text59">computeMatrix</text> + </g> + <!-- 3->12 --> + <g + id="edge25" + class="edge"> + <title + id="title62">3->12</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M143.71,-503.7C145.36,-495.98 147.35,-486.71 149.19,-478.11" + id="path64" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="152.66,-478.62 151.33,-468.1 145.82,-477.15 152.66,-478.62" + id="polygon66" /> + </g> + <!-- 24 --> + <g + id="node25" + class="node" + transform="translate(0.51906781,43.601696)"> + <title + id="title69">24</title> + <path + d="m 497,-468 c 0,0 -50,0 -50,0 -6,0 -12,6 -12,12 0,0 0,12 0,12 0,6 6,12 12,12 0,0 50,0 50,0 6,0 12,-6 12,-12 0,0 0,-12 0,-12 0,-6 -6,-12 -12,-12" + id="path71" + inkscape:connector-curvature="0" + style="fill:none;stroke:#56a2d8;stroke-width:2" /> + <text + x="472" + y="-447.5" + font-size="10.00" + id="text73" + style="font-size:10px;font-family:sans;text-anchor:middle">igv_session</text> + </g> + <!-- 3->24 --> + <g + id="edge38" + class="edge" + transform="matrix(1.0301602,0,0,1.5542929,-5.1976541,286.29348)"> + <title + id="title76">3->24</title> + <path + d="m 182.72,-511.99 c 62.18,13.11 177.21,37.36 241.9,51" + id="path78" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="424.05,-457.53 425.5,-464.38 434.56,-458.89 " + id="polygon80" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <!-- 4 --> + <g + id="node5" + class="node"> + <title + id="title83">4</title> + <path + fill="none" + stroke="#d87d56" + stroke-width="2" + d="M422,-756C422,-756 316,-756 316,-756 310,-756 304,-750 304,-744 304,-744 304,-732 304,-732 304,-726 310,-720 316,-720 316,-720 422,-720 422,-720 428,-720 434,-726 434,-732 434,-732 434,-744 434,-744 434,-750 428,-756 422,-756" + id="path85" /> + <text + text-anchor="middle" + x="369" + y="-735.5" + font-family="sans" + font-size="10.00" + id="text87">remove_biasedRegions</text> + </g> + <!-- 4->3 --> + <g + id="edge17" + class="edge" + transform="matrix(1.0193732,0,0,1.0140883,-2.515932,7.5643282)"> + <title + id="title90">4->3</title> + <path + d="M 303.89,-719.94 C 250.94,-702.33 179.4,-669.18 144,-612 c -11.35,18.33 -11.52,43.09 -9.33,61.84" + id="path92" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="136.12,-540.17 131.22,-549.56 138.15,-550.57 " + id="polygon94" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <!-- 9 --> + <g + id="node10" + class="node"> + <title + id="title97">9</title> + <path + fill="none" + stroke="#56d8d8" + stroke-width="2" + d="M291,-612C291,-612 165,-612 165,-612 159,-612 153,-606 153,-600 153,-600 153,-588 153,-588 153,-582 159,-576 165,-576 165,-576 291,-576 291,-576 297,-576 303,-582 303,-588 303,-588 303,-600 303,-600 303,-606 297,-612 291,-612" 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398.5,-252 392.5,-252" + id="path127" /> + <text + text-anchor="middle" + x="349" + y="-231.5" + font-family="sans" + font-size="10.00" + id="text129">insert_size_metrics</text> + </g> + <!-- 4->13 --> + <g + id="edge26" + class="edge"> + <title + id="title132">4->13</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M369,-719.95C369,-693.29 369,-640.11 369,-595 369,-595 369,-595 369,-521 369,-425.71 357.81,-312.99 352.17,-262.2" + id="path134" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="355.63,-261.6 351.03,-252.06 348.67,-262.39 355.63,-261.6" + id="polygon136" /> + </g> + <!-- 14 --> + <g + id="node15" + class="node"> + <title + id="title139">14</title> + <path + fill="none" + stroke="#8fd856" + stroke-width="2" + d="M439,-684C439,-684 409,-684 409,-684 403,-684 397,-678 397,-672 397,-672 397,-660 397,-660 397,-654 403,-648 409,-648 409,-648 439,-648 439,-648 445,-648 451,-654 451,-660 451,-660 451,-672 451,-672 451,-678 445,-684 439,-684" + id="path141" /> + <text + text-anchor="middle" + x="424" + y="-663.5" + font-family="sans" + font-size="10.00" + id="text143">spp</text> + </g> + <!-- 4->14 --> + <g + id="edge27" + class="edge"> + <title + id="title146">4->14</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M382.6,-719.7C389.12,-711.39 397.07,-701.28 404.25,-692.14" + id="path148" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="407.13,-694.13 410.56,-684.1 401.63,-689.81 407.13,-694.13" + id="polygon150" /> + </g> + <!-- 16 --> + <g + id="node17" + class="node" + transform="translate(28.827861,63.28178)"> + <title + id="title153">16</title> + <path + d="m 549,-684 c 0,0 -38,0 -38,0 -6,0 -12,6 -12,12 0,0 0,12 0,12 0,6 6,12 12,12 0,0 38,0 38,0 6,0 12,-6 12,-12 0,0 0,-12 0,-12 0,-6 -6,-12 -12,-12" + id="path155" + inkscape:connector-curvature="0" + style="fill:none;stroke:#56d8c9;stroke-width:2" /> + <text + x="530" + y="-663.5" + font-size="10.00" + id="text157" 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id="path169" /> + <text + text-anchor="middle" + x="741" + y="-303.5" + font-family="sans" + font-size="10.00" + id="text171">feature_counts</text> + </g> + <!-- 4->21 --> + <g + id="edge35" + class="edge"> + <title + id="title174">4->21</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M434.41,-726.29C542.6,-706.71 747,-660.98 747,-595 747,-595 747,-595 747,-449 747,-408.96 744.59,-362.63 742.82,-334.07" + id="path176" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="746.31,-333.8 742.19,-324.04 739.33,-334.24 746.31,-333.8" + id="polygon178" /> + </g> + <!-- 5 --> + <g + id="node6" + class="node"> + <title + id="title181">5</title> + <path + fill="none" + stroke="#d85656" + stroke-width="2" + d="M406,-828C406,-828 332,-828 332,-828 326,-828 320,-822 320,-816 320,-816 320,-804 320,-804 320,-798 326,-792 332,-792 332,-792 406,-792 406,-792 412,-792 418,-798 418,-804 418,-804 418,-816 418,-816 418,-822 412,-828 406,-828" + id="path183" /> + 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id="text199">bowtie2_mapping</text> + </g> + <!-- 6->5 --> + <g + id="edge19" + class="edge"> + <title + id="title202">6->5</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M369,-863.7C369,-855.98 369,-846.71 369,-838.11" + id="path204" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="372.5,-838.1 369,-828.1 365.5,-838.1 372.5,-838.1" + id="polygon206" /> + </g> + <!-- 7 --> + <g + id="node8" + class="node"> + <title + id="title209">7</title> + <path + fill="none" + stroke="#56b1d8" + stroke-width="2" + d="M340.5,-972C340.5,-972 305.5,-972 305.5,-972 299.5,-972 293.5,-966 293.5,-960 293.5,-960 293.5,-948 293.5,-948 293.5,-942 299.5,-936 305.5,-936 305.5,-936 340.5,-936 340.5,-936 346.5,-936 352.5,-942 352.5,-948 352.5,-948 352.5,-960 352.5,-960 352.5,-966 346.5,-972 340.5,-972" + id="path211" /> + <text + text-anchor="middle" + x="323" + y="-951.5" + font-family="sans" + font-size="10.00" + id="text213">cutadapt</text> + </g> + <!-- 7->6 --> + <g + id="edge21" + class="edge"> + <title + id="title216">7->6</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M334.37,-935.7C339.72,-927.56 346.2,-917.69 352.11,-908.7" + id="path218" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="355.19,-910.38 357.76,-900.1 349.34,-906.54 355.19,-910.38" + id="polygon220" /> + </g> + <!-- 8 --> + <g + id="node9" + class="node"> + <title + id="title223">8</title> + <path + fill="none" + stroke="#c6d856" + stroke-width="2" + d="M447,-972C447,-972 383,-972 383,-972 377,-972 371,-966 371,-960 371,-960 371,-948 371,-948 371,-942 377,-936 383,-936 383,-936 447,-936 447,-936 453,-936 459,-942 459,-948 459,-948 459,-960 459,-960 459,-966 453,-972 447,-972" + id="path225" /> + <text + text-anchor="middle" + x="415" + y="-951.5" + font-family="sans" + font-size="10.00" + id="text227">bowtie2_index</text> + </g> + <!-- 8->6 --> + <g + id="edge20" + class="edge"> + <title + id="title230">8->6</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M403.63,-935.7C398.28,-927.56 391.8,-917.69 385.89,-908.7" + id="path232" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="388.66,-906.54 380.24,-900.1 382.81,-910.38 388.66,-906.54" + id="polygon234" /> + </g> + <!-- 9->1 --> + <g + id="edge4" + class="edge"> + <title + id="title237">9->1</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M224.58,-575.73C212.34,-508.19 177.93,-259.87 308,-144 343.29,-112.56 397.53,-99.73 433.62,-94.52" + id="path239" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="434.29,-97.97 443.75,-93.19 433.38,-91.03 434.29,-97.97" + id="polygon241" /> + </g> + <!-- 10->1 --> + <g + id="edge11" + class="edge"> + <title + id="title244">10->1</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M289.45,-287.94C281.37,-269.26 272.13,-238.91 284,-216 315.05,-156.08 389.4,-120.09 434.44,-103.04" + id="path246" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="435.66,-106.31 443.85,-99.59 433.25,-99.74 435.66,-106.31" + id="polygon248" /> + </g> + <!-- 11 --> + <g + id="node12" + class="node"> + <title + id="title251">11</title> + <path + fill="none" + stroke="#56d87b" + stroke-width="2" + d="M185,-324C185,-324 129,-324 129,-324 123,-324 117,-318 117,-312 117,-312 117,-300 117,-300 117,-294 123,-288 129,-288 129,-288 185,-288 185,-288 191,-288 197,-294 197,-300 197,-300 197,-312 197,-312 197,-318 191,-324 185,-324" + id="path253" /> + <text + text-anchor="middle" + x="157" + y="-303.5" + font-family="sans" + font-size="10.00" + id="text255">plotHeatmap</text> + </g> + <!-- 11->1 --> + <g + id="edge8" + class="edge"> + <title + id="title258">11->1</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M157.55,-287.91C159.58,-254.8 168.99,-181.86 212,-144 244.55,-115.35 370.19,-100.12 433.73,-94.1" + id="path260" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="434.11,-97.58 443.74,-93.19 433.47,-90.61 434.11,-97.58" + id="polygon262" /> + </g> + <!-- 12->11 --> + <g + id="edge24" + class="edge"> + <title + id="title265">12->11</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M155.24,-431.87C155.58,-407.67 156.21,-363.21 156.61,-334.39" + id="path267" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="160.12,-334.24 156.76,-324.19 153.12,-334.14 160.12,-334.24" + id="polygon269" /> + </g> + <!-- 13->1 --> + <g + id="edge6" + class="edge"> + <title + id="title272">13->1</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M361.63,-215.82C375.25,-197.57 397.84,-168.06 419,-144 427.51,-134.32 437.31,-124.11 446.09,-115.27" + id="path274" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="448.56,-117.75 453.17,-108.21 443.62,-112.79 448.56,-117.75" + id="polygon276" /> + </g> + <!-- 14->1 --> + <g + id="edge16" + class="edge"> + <title + id="title279">14->1</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M423.43,-647.73C422.3,-609.04 420.36,-512.51 426,-432 434.21,-314.76 456.39,-176.24 466.21,-118.45" + id="path281" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="469.71,-118.76 467.95,-108.31 462.81,-117.58 469.71,-118.76" + id="polygon283" /> + </g> + <!-- 15 --> + <g + id="node16" + class="node" + transform="translate(-1.4274365,51.083687)"> + <title + id="title286">15</title> + <path + d="m 575,-612 c 0,0 -30,0 -30,0 -6,0 -12,6 -12,12 0,0 0,12 0,12 0,6 6,12 12,12 0,0 30,0 30,0 6,0 12,-6 12,-12 0,0 0,-12 0,-12 0,-6 -6,-12 -12,-12" + id="path288" + inkscape:connector-curvature="0" + style="fill:none;stroke:#566bd8;stroke-width:2" /> + <text + x="560" + y="-591.5" + font-size="10.00" + id="text290" + style="font-size:10px;font-family:sans;text-anchor:middle">seacr</text> + </g> + <!-- 15->1 --> + <g + id="edge15" + class="edge" + transform="matrix(1,0,0,0.92616266,0,-7.1614837)"> + <title + id="title293">15->1</title> + <path + d="m 587.19,-577.7 c 14.25,9.25 30.95,22.25 41.81,37.7 46.37,65.99 33.63,100.05 23,180 -13.25,99.63 1.75,142.68 -67,216 -20.6,21.97 -52.11,35.65 -76.79,43.6" + id="path295" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="498.44,-97.43 507,-103.69 509.03,-96.99 " + id="polygon297" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <!-- 17 --> + <g + id="node18" + class="node"> + <title + id="title300">17</title> + <path + fill="none" + stroke="#78d856" + stroke-width="2" + d="M867,-396C867,-396 787,-396 787,-396 781,-396 775,-390 775,-384 775,-384 775,-372 775,-372 775,-366 781,-360 787,-360 787,-360 867,-360 867,-360 873,-360 879,-366 879,-372 879,-372 879,-384 879,-384 879,-390 873,-396 867,-396" + id="path302" /> + <text + text-anchor="middle" + x="827" + y="-375.5" + font-family="sans" + font-size="10.00" + id="text304">stats_peakCalling</text> + </g> + <!-- 15->17 --> + <g + id="edge30" + class="edge" + transform="matrix(0.99978124,0,0,0.77164887,0.1784433,-90.497835)"> + <title + id="title307">15->17</title> + <path + d="m 587.14,-585.38 c 26.6,8.33 67.46,23.47 97.86,45.38 53.29,38.41 100.51,100.24 124.76,135.04" + id="path309" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="815.7,-396.31 807.15,-402.57 812.92,-406.54 " + id="polygon311" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <!-- 18 --> + <g + id="node19" + class="node" + transform="translate(0,40.5)"> + <title + id="title314">18</title> + <path + d="m 608,-540 c 0,0 -96,0 -96,0 -6,0 -12,6 -12,12 0,0 0,12 0,12 0,6 6,12 12,12 0,0 96,0 96,0 6,0 12,-6 12,-12 0,0 0,-12 0,-12 0,-6 -6,-12 -12,-12" + id="path316" + inkscape:connector-curvature="0" + style="fill:none;stroke:#d8b456;stroke-width:2" /> + <text + x="560" + y="-519.5" + font-size="10.00" + id="text318" + style="font-size:10px;font-family:sans;text-anchor:middle">intersectionApproach</text> + </g> + <!-- 15->18 --> + <g + id="edge31" + class="edge" + transform="matrix(1,0,0,0.62455066,0,-164.22668)"> + <title + id="title321">15->18</title> + <path + d="m 560,-575.7 c 0,7.72 0,16.99 0,25.59" + id="path323" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="563.5,-550.1 560,-540.1 556.5,-550.1 " + id="polygon325" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <!-- 15->24 --> + <g + id="edge40" + class="edge" + transform="matrix(0.95846716,0,0,1.0475054,19.500476,63.737886)"> + <title + id="title328">15->24</title> + <path + d="m 532.9,-578.55 c -14.6,9.16 -31.66,22.33 -41.9,38.55 -11.7,18.54 -16.3,43.13 -18.06,61.77" + id="path330" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="476.42,-477.76 472.2,-468.04 469.43,-478.27 " + id="polygon332" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <!-- 16->15 --> + <!-- 17->1 --> + <g + id="edge2" + class="edge"> + <title + id="title342">17->1</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M830.69,-359.85C838.91,-316.52 853.5,-201.99 793,-144 752.77,-105.43 584.18,-94.84 508.3,-92.01" + id="path344" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="508.35,-88.5 498.23,-91.65 508.1,-95.5 508.35,-88.5" + id="polygon346" /> + </g> + <!-- 18->1 --> + <g + id="edge14" + class="edge" + transform="matrix(1,0,0,0.8945171,0,-11.401646)"> + <title + id="title349">18->1</title> + <path + d="M 553.02,-503.86 C 539.05,-467.97 509,-382.05 509,-307 c 0,0 0,0 0,74 0,41.37 -15.23,87.28 -26.41,115.39" + id="path351" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="478.69,-108.09 479.24,-118.67 485.72,-116.02 " + id="polygon353" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <!-- 19 --> + <g + id="node20" + class="node" + transform="translate(0,43.5)"> + <title + id="title356">19</title> + <path + d="m 631,-468 c 0,0 -54,0 -54,0 -6,0 -12,6 -12,12 0,0 0,12 0,12 0,6 6,12 12,12 0,0 54,0 54,0 6,0 12,-6 12,-12 0,0 0,-12 0,-12 0,-6 -6,-12 -12,-12" + id="path358" + inkscape:connector-curvature="0" + style="fill:none;stroke:#d8c356;stroke-width:2" /> + <text + x="604" + y="-447.5" + font-size="10.00" + id="text360" + style="font-size:10px;font-family:sans;text-anchor:middle">union_peaks</text> + </g> + <!-- 18->19 --> + <g + id="edge32" + class="edge" + transform="translate(0,40.5)"> + <title + id="title363">18->19</title> + <path + d="m 570.88,-503.7 c 5.11,8.14 11.32,18.01 16.96,27" + id="path365" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="590.89,-478.43 593.25,-468.1 584.96,-474.71 " + id="polygon367" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <!-- 18->24 --> + <g + id="edge39" + class="edge" + transform="translate(-3.6334747,41.784959)"> + <title + id="title370">18->24</title> + <path + d="m 538.25,-503.7 c -11.09,8.82 -24.72,19.67 -36.74,29.23" + id="path372" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="493.5,-468.1 499.15,-477.07 503.51,-471.59 " + id="polygon374" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <!-- 19->1 --> + <g + id="edge5" + class="edge" + transform="matrix(1,0,0,0.86321518,0,-14.79191)"> + <title + id="title377">19->1</title> + <path + d="m 589.02,-431.97 c -7.96,9.88 -17.25,22.92 -23.02,35.97 -16.35,36.99 -19,48.55 -19,89 0,0 0,0 0,74 0,40.97 -3.66,53.44 -24,89 -6.04,10.56 -14.69,20.53 -23.21,28.92" + id="path379" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="492.41,-108.14 497.3,-117.54 502.09,-112.44 " + id="polygon381" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <!-- 20 --> + <g + id="node21" + class="node" + transform="translate(-1.8167374,46.45657)"> + <title + id="title384">20</title> + <path + d="m 631,-396 c 0,0 -44,0 -44,0 -6,0 -12,6 -12,12 0,0 0,12 0,12 0,6 6,12 12,12 0,0 44,0 44,0 6,0 12,-6 12,-12 0,0 0,-12 0,-12 0,-6 -6,-12 -12,-12" + id="path386" + inkscape:connector-curvature="0" + style="fill:none;stroke:#59d856;stroke-width:2" /> + <text + x="609" + y="-375.5" + font-size="10.00" + id="text388" + style="font-size:10px;font-family:sans;text-anchor:middle">bed_to_gff</text> + </g> + <!-- 19->20 --> + <g + id="edge33" + class="edge" + transform="translate(0,43.5)"> + <title + id="title391">19->20</title> + <path + d="m 605.24,-431.7 c 0.55,7.72 1.21,16.99 1.82,25.59" + id="path393" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="603.57,-405.83 610.56,-406.33 607.78,-396.1 " + id="polygon395" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <!-- 20->1 --> + <g + id="edge7" + class="edge" + transform="matrix(1,0,0,0.81829449,0,-18.174185)"> + <title + id="title398">20->1</title> + <path + d="m 609.95,-359.94 c 1.43,41.19 -0.18,147.75 -48.95,215.94 -13.18,18.42 -34.92,31.48 -53.73,40.03" + id="path400" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="505.86,-107.17 508.61,-100.74 498.04,-100.02 " + id="polygon402" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <!-- 20->21 --> + <g + id="edge34" + class="edge" + transform="matrix(0.80317042,0,0,0.69574634,127.09591,-81.664274)"> + <title + id="title405">20->21</title> + <path + d="m 641.29,-359.88 c 17.58,9.33 39.52,20.96 58.34,30.94" + id="path407" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="698.11,-325.78 701.39,-331.97 708.59,-324.19 " + id="polygon409" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <!-- 21->1 --> + <g + id="edge12" + class="edge"> + <title + id="title412">21->1</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M729.19,-287.79C722.51,-277.63 714.26,-264.38 708,-252 684.7,-205.89 703.52,-178.43 665,-144 621.11,-104.78 550.88,-94.23 508.05,-91.6" + id="path414" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="508.21,-88.1 498.04,-91.1 507.86,-95.09 508.21,-88.1" + id="polygon416" /> + </g> + <!-- 23 --> + <g + id="node24" + class="node"> + <title + id="title419">23</title> + <path + fill="none" + stroke="#56d86b" + stroke-width="2" + d="M787,-252C787,-252 729,-252 729,-252 723,-252 717,-246 717,-240 717,-240 717,-228 717,-228 717,-222 723,-216 729,-216 729,-216 787,-216 787,-216 793,-216 799,-222 799,-228 799,-228 799,-240 799,-240 799,-246 793,-252 787,-252" + id="path421" /> + <text + text-anchor="middle" + x="758" + y="-231.5" + font-family="sans" + font-size="10.00" + id="text423">chipflowr_init</text> + </g> + <!-- 21->23 --> + <g + id="edge37" + class="edge"> + <title + id="title426">21->23</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M745.2,-287.7C747.1,-279.9 749.38,-270.51 751.48,-261.83" + id="path428" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="754.89,-262.65 753.85,-252.1 748.08,-261 754.89,-262.65" + id="polygon430" /> + </g> + <!-- 22 --> + <g + id="node23" + class="node"> + <title + id="title433">22</title> + <path + fill="none" + stroke="#d88d56" + stroke-width="2" + d="M771.5,-180C771.5,-180 734.5,-180 734.5,-180 728.5,-180 722.5,-174 722.5,-168 722.5,-168 722.5,-156 722.5,-156 722.5,-150 728.5,-144 734.5,-144 734.5,-144 771.5,-144 771.5,-144 777.5,-144 783.5,-150 783.5,-156 783.5,-156 783.5,-168 783.5,-168 783.5,-174 777.5,-180 771.5,-180" + id="path435" /> + <text + text-anchor="middle" + x="753" + y="-159.5" + font-family="sans" + font-size="10.00" + id="text437">chipflowr</text> + </g> + <!-- 22->1 --> + <g + id="edge10" + class="edge"> + <title + id="title440">22->1</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M722.48,-150.07C716.08,-147.93 709.35,-145.8 703,-144 634.82,-124.68 553.85,-107.45 507.84,-98.19" + id="path442" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="508.51,-94.76 498.02,-96.23 507.14,-101.62 508.51,-94.76" + id="polygon444" /> + </g> + <!-- 23->22 --> + <g + id="edge36" + class="edge"> + <title + id="title447">23->22</title> + <path + fill="none" + stroke="grey" + stroke-width="2" + d="M756.76,-215.7C756.21,-207.98 755.55,-198.71 754.94,-190.11" + id="path449" /> + <polygon + fill="grey" + stroke="grey" + stroke-width="2" + points="758.43,-189.83 754.22,-180.1 751.44,-190.33 758.43,-189.83" + id="polygon451" /> + </g> + <!-- 24->1 --> + <g + id="edge9" + class="edge" + transform="matrix(1,0,0,0.86298604,0,-14.804358)"> + <title + id="title454">24->1</title> + <path + d="m 471.8,-431.95 c -0.29,26.66 -0.8,79.83 -0.8,124.95 0,0 0,0 0,74 0,40 0,86.35 0,114.92" + id="path456" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="471,-108.05 467.5,-118.05 474.5,-118.05 " + id="polygon458" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <g + transform="translate(-58.408347,-291.87977)" + id="node21-3" + class="node"> + <title + id="title384-6">20</title> + <path + style="fill:none;stroke:#59d856;stroke-width:2.60489249" + inkscape:connector-curvature="0" + d="m 645.36524,-396 c 0,0 -74.64011,0 -74.64011,0 -10.17819,0 -20.35639,6 -20.35639,12 0,0 0,12 0,12 0,6 10.1782,12 20.35639,12 0,0 74.64011,0 74.64011,0 10.17819,0 20.35639,-6 20.35639,-12 0,0 0,-12 0,-12 0,-6 -10.1782,-12 -20.35639,-12" + id="path386-7" /> + <text + style="font-size:10px;font-family:sans;text-anchor:middle" + x="607.5" + y="-375.5" + font-size="10.00" + id="text388-5">compute_scale_factor</text> + </g> + <g + id="edge31-3" + class="edge" + transform="matrix(1,0,0,0.51884163,-1.1435182,-283.9148)"> + <title + id="title321-5">15->18</title> + <path + d="m 560,-575.7 c 0,7.72 0,16.99 0,25.59" + id="path323-6" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="560,-540.1 556.5,-550.1 563.5,-550.1 " + id="polygon325-2" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + <g + id="edge31-3-9" + class="edge" + transform="matrix(1,0,0,0.72296942,-0.29235322,-233.73195)"> + <title + id="title321-5-1">15->18</title> + <path + d="m 560,-575.7 c 0,7.72 0,16.99 0,25.59" + id="path323-6-2" + inkscape:connector-curvature="0" + style="fill:none;stroke:#808080;stroke-width:2" /> + <polygon + points="563.5,-550.1 560,-540.1 556.5,-550.1 " + id="polygon325-2-7" + style="fill:#808080;stroke:#808080;stroke-width:2" /> + </g> + </g> </svg>