WIP on #184

WIP on #184

fixes #185

WIP on #174 and #175

WIP on #174
this runs on a set of selected compounds:
- compute compound properties
- cache compound properties
- compute drugbank similarity
- validate the compound(s)
- compute LE-LLE and PCA plots

bad things happening like in
https://gitlab.pasteur.fr/ippidb/ippidb-web/-/jobs/46983

had to update the icon, as external-link is now pro-only

basically, this adds:
- a CI step to run flake8, _including_ the black plugin to check
  whether or not files need black reformatting
- add flake8 and black to dependencies
- reformat files and correct style so that current code passes

Adding a live settings app that save in db some settings, adding command in admin ui to change settings related to access to contribution mode
closes #112

Former-commit-id: afcd004395586bedc7b56193c0a63167346bd2f5

see #96


Former-commit-id: 90abafc4f53301e38e9fac6171416587aba94288

this results in a timeout due to the size of MDDR
closes #76


Former-commit-id: fa4dbc0f95f38a5ff92b4e727d0d484e3d8a173c

esp. useful now that compound ids are permanent (cf #51)


Former-commit-id: 3eee58ba2afdb7a62b68eaa569cbdfe3f82747f9

Former-commit-id: e4a2b89495247a4954b8046c445d85df5888f0b5

Former-commit-id: 00c06a433097c92cee328894c321325101bc9d43

fixes #21

closes #35

(closes #9)