abii.md

title: AbiI
layout: article
tableColumns:
    article:
      doi: 10.1016/j.mib.2005.06.006
      abstract: |
        Abortive infection (Abi) systems, also called phage exclusion, block phage multiplication and cause premature bacterial cell death upon phage infection. This decreases the number of progeny particles and limits their spread to other cells allowing the bacterial population to survive. Twenty Abi systems have been isolated in Lactococcus lactis, a bacterium used in cheese-making fermentation processes, where phage attacks are of economical importance. Recent insights in their expression and mode of action indicate that, behind diverse phenotypic and molecular effects, lactococcal Abis share common traits with the well-studied Escherichia coli systems Lit and Prr. Abis are widespread in bacteria, and recent analysis indicates that Abis might have additional roles other than conferring phage resistance.
    Sensor: Unknown
    Activator: Unknown
    Effector: Unknown

AbiI

Example of genomic structure

The AbiI system is composed of one protein: AbiI.

Here is an example found in the RefSeq database:

AbiI system in the genome of Enterococcus faecalis (GCF_002814115.1) is composed of 1 protein: AbiI (WP_002367720.1).

Distribution of the system among prokaryotes

The AbiI system is present in a total of 8 different species.

Among the 22k complete genomes of RefSeq, this system is present in 8 genomes (0.0 %).

Proportion of genome encoding the AbiI system for the 14 phyla with more than 50 genomes in the RefSeq database.

Structure

AbiI

::molstar-pdbe-plugin

height: 700 dataUrl: /abii/AbiI__AbiI-plddts_90.31131.pdb

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Experimental validation

graph LR; Chopin_2005[Chopin et al., 2005] --> Origin_0 Origin_0[lactococcal plasmid AAB66882.1] --> Expressed_0[lactococci] Expressed_0[lactococci] ----> 936 & c2 subgraph Title1[Reference] Chopin_2005 end subgraph Title2[System origin] Origin_0 end subgraph Title3[Expression species] Expressed_0 end subgraph Title4[Phage infected] 936 c2 end style Title1 fill:none,stroke:none,stroke-width:none style Title2 fill:none,stroke:none,stroke-width:none style Title3 fill:none,stroke:none,stroke-width:none style Title4 fill:none,stroke:none,stroke-width:none ## Relevant abstracts

::relevant-abstracts

items: - doi: 10.1023/A:1002027321171 - doi: 10.1016/j.mib.2005.06.006

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