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fltesson authored89180a7b
title: AbiJ
layout: article
tableColumns:
article:
doi: 10.1016/j.mib.2005.06.006
abstract: |
Abortive infection (Abi) systems, also called phage exclusion, block phage multiplication and cause premature bacterial cell death upon phage infection. This decreases the number of progeny particles and limits their spread to other cells allowing the bacterial population to survive. Twenty Abi systems have been isolated in Lactococcus lactis, a bacterium used in cheese-making fermentation processes, where phage attacks are of economical importance. Recent insights in their expression and mode of action indicate that, behind diverse phenotypic and molecular effects, lactococcal Abis share common traits with the well-studied Escherichia coli systems Lit and Prr. Abis are widespread in bacteria, and recent analysis indicates that Abis might have additional roles other than conferring phage resistance.
Sensor: Unknown
Activator: Unknown
Effector: Unknown
PFAM: PF14355
contributors:
- Florian Tesson
relevantAbstracts:
- doi: 10.1023/A:1002027321171
- doi: 10.1016/j.mib.2005.06.006
- doi: 10.1111/j.1574-6968.1997.tb10185.xAbiJ
Description
AbiJ was discovered in 1997 on a Lactococcus lactis biovar. diacetylactis :ref{doi=10.1111/j.1574-6968.1997.tb10185.x}.
AbiJ is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry :ref{doi=10.1016/j.mib.2005.06.006}. AbiJ is classified as abortive infection in :ref{doi=10.1016/j.mib.2023.102312}.
AbiJ is composed of one protein AbiJ. AbiJ has some homology with AbiC (PF14355).
Molecular mechanism
As far as we are aware, the molecular mechanism is unknown.
Example of genomic structure
The AbiJ is composed of 1 protein: AbiJ.
Here is an example found in the RefSeq database:
The AbiJ system in Marinobacter sp. LQ44 (GCF_001447155.2, NZ_CP014754) is composed of 1 protein: AbiJ (WP_058091398.1)
Distribution of the system among prokaryotes
Among the 22,803 complete genomes of RefSeq, the AbiJ is detected in 686 genomes (3.01 %).
The system was detected in 261 different species.
Proportion of genome encoding the AbiJ system for the 14 phyla with more than 50 genomes in the RefSeq database.
Structure
AbiJ
Example 1
::molstar-pdbe-plugin
height: 700 dataUrls:
- /abij/AbiJ__AbiJ.cif
::