abig.md

title: AbiG
layout: article
tableColumns:
    article:
      doi: 10.1016/j.mib.2005.06.006
      abstract: |
        Abortive infection (Abi) systems, also called phage exclusion, block phage multiplication and cause premature bacterial cell death upon phage infection. This decreases the number of progeny particles and limits their spread to other cells allowing the bacterial population to survive. Twenty Abi systems have been isolated in Lactococcus lactis, a bacterium used in cheese-making fermentation processes, where phage attacks are of economical importance. Recent insights in their expression and mode of action indicate that, behind diverse phenotypic and molecular effects, lactococcal Abis share common traits with the well-studied Escherichia coli systems Lit and Prr. Abis are widespread in bacteria, and recent analysis indicates that Abis might have additional roles other than conferring phage resistance.
    Sensor: Unknown
    Activator: Unknown
    Effector: Unknown
    PFAM: PF10899, PF16873
relevantAbstracts:
    - doi: 10.1023/A:1002027321171
    - doi: 10.1016/j.mib.2005.06.006

AbiG

Example of genomic structure

The AbiG is composed of 2 proteins: AbiGi and AbiGii.

Here is an example found in the RefSeq database:

The AbiG system in Staphylococcus simulans (GCF_900474685.1, NZ_LS483313) is composed of 2 proteins AbiGi (WP_103364194.1) AbiGii (WP_070462993.1)

Distribution of the system among prokaryotes

Among the 22,803 complete genomes of RefSeq, the AbiG is detected in 32 genomes (0.14 %).

The system was detected in 22 different species.

Proportion of genome encoding the AbiG system for the 14 phyla with more than 50 genomes in the RefSeq database.

Structure

AbiG

Example 1

::molstar-pdbe-plugin

height: 700 dataUrls:

• /abig/AbiG.AbiG__AbiGi.0.V.cif
• /abig/AbiG.AbiG__AbiGii.0.V.cif

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::