From 031be32ffeb9d44843248fade629dae71e6dd95c Mon Sep 17 00:00:00 2001 From: Jean CURY <jean.cury@pasteur.fr> Date: Wed, 29 Nov 2023 18:03:41 +0100 Subject: [PATCH] Update lamassu-fam.md --- content/3.defense-systems/lamassu-fam.md | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/content/3.defense-systems/lamassu-fam.md b/content/3.defense-systems/lamassu-fam.md index 3e75d0d8..f937a62d 100644 --- a/content/3.defense-systems/lamassu-fam.md +++ b/content/3.defense-systems/lamassu-fam.md @@ -28,7 +28,7 @@ The original types of Lamassu systems are Lamassu Type 1 :ref{doi=10.1126/scienc Lamassu has been suggested to be a large family of defense systems, that can be classified into multiple subtypes :ref{doi=10.1016/j.chom.2022.09.017}. -These systems all encode the *lmuB* gene, and in most cases also comprise *lmuC*. In addition to these two core genes, Lamassu systems of various subtypes encode a third protein, hypothesized to be the Abi effector protein. This effector  can be proteins encoding endonuclease domains, SIR2-domains, or even hydrolase domains :ref{doi=10.1016/j.chom.2022.09.017}. Systems of the extended Lamassu-family can be found in 10% of prokaryotic genomes :ref{doi=10.1016/j.chom.2022.09.017}. +These systems all encode the *lmuB* gene, and in most cases also comprise *lmuC*. In addition to these two core genes, Lamassu systems of various subtypes encode a third protein, hypothesized to be the Abi effector protein :ref{doi=10.1101/2022.05.11.491447}. This effector  can be proteins encoding endonuclease domains, SIR2-domains, or even hydrolase domains :ref{doi=10.1016/j.chom.2022.09.017}. Systems of the extended Lamassu-family can be found in 10% of prokaryotic genomes :ref{doi=10.1016/j.chom.2022.09.017}. Lamassu were also described as DdmABC in *Vibrio cholerae* :ref{doi=10.1038/s41586-022-04546-y, 10.1101/2022.11.18.517080}. They were found to be antiplasmids and thus to eliminate plasmids from seventh pandemic *Vibrio cholerae* :ref{doi=10.1038/s41586-022-04546-y}. -- GitLab