diff --git a/content/3.defense-systems/rst_tir-nlr.md b/content/3.defense-systems/rst_tir-nlr.md index 9b29b9e6dbe43b38000d3859b2fd9897a88ea958..1060769b9bbe223423179d2d2f379e83d3f453e6 100644 --- a/content/3.defense-systems/rst_tir-nlr.md +++ b/content/3.defense-systems/rst_tir-nlr.md @@ -10,9 +10,24 @@ tableColumns: Activator: Unknown Effector: Unknown PFAM: PF13676 +contributors: + - Lucas Paoli +relevantAbstracts: + - doi: 10.1016/j.chom.2022.02.018 --- # Rst_TIR-NLR + +## Description + +The Rst_TIR-NLR system is named after the first author of the paper describing it (Rousset et al. 2022) and the domains of the only protein it contains (TIR, toll-interleukin-1 receptor, and NLR, nucleotide-binding leucine rich repeat receptor) :ref{doi=10.1016/j.chom.2022.02.018}. + +This system is very similar to other bacterial defense systems: bNACHT (https://defense-finder.pasteur.cloud/wiki/defense-systems/nlr), CARD_NLR (https://defense-finder.pasteur.cloud/wiki/defense-systems/card_nlr), Avs (AVAST) (https://defense-finder.pasteur.cloud/wiki/defense-systems/avs). + +## Molecular mechanisms + +As far as we are aware, the molecular mechanism is unknown. However, the molecular mechanism of closely related systems was previously studied. See bNACHT (https://defense-finder.pasteur.cloud/wiki/defense-systems/nlr), CARD_NLR (https://defense-finder.pasteur.cloud/wiki/defense-systems/card_nlr) and Avs (AVAST) (https://defense-finder.pasteur.cloud/wiki/defense-systems/avs) + ## Example of genomic structure The Rst_TIR-NLR system is composed of one protein: TIR. @@ -73,13 +88,3 @@ end style Title3 fill:none,stroke:none,stroke-width:none style Title4 fill:none,stroke:none,stroke-width:none </mermaid> -## Relevant abstracts - -::relevant-abstracts ---- -items: - - doi: 10.1016/j.chom.2022.02.018 - ---- -:: -