From 03cd1011b8845937926f0857713a0cdd0ab6142b Mon Sep 17 00:00:00 2001
From: Lucas PAOLI <lucas.paoli@pasteur.fr>
Date: Mon, 8 Jan 2024 11:27:31 +0100
Subject: [PATCH] Update rst_tir-nlr.md according to Hackaton guidelines,
see...
---
content/3.defense-systems/rst_tir-nlr.md | 25 ++++++++++++++----------
1 file changed, 15 insertions(+), 10 deletions(-)
diff --git a/content/3.defense-systems/rst_tir-nlr.md b/content/3.defense-systems/rst_tir-nlr.md
index 9b29b9e6..1060769b 100644
--- a/content/3.defense-systems/rst_tir-nlr.md
+++ b/content/3.defense-systems/rst_tir-nlr.md
@@ -10,9 +10,24 @@ tableColumns:
Activator: Unknown
Effector: Unknown
PFAM: PF13676
+contributors:
+ - Lucas Paoli
+relevantAbstracts:
+ - doi: 10.1016/j.chom.2022.02.018
---
# Rst_TIR-NLR
+
+## Description
+
+The Rst_TIR-NLR system is named after the first author of the paper describing it (Rousset et al. 2022) and the domains of the only protein it contains (TIR, toll-interleukin-1 receptor, and NLR, nucleotide-binding leucine rich repeat receptor) :ref{doi=10.1016/j.chom.2022.02.018}.
+
+This system is very similar to other bacterial defense systems: bNACHT (https://defense-finder.pasteur.cloud/wiki/defense-systems/nlr), CARD_NLR (https://defense-finder.pasteur.cloud/wiki/defense-systems/card_nlr), Avs (AVAST) (https://defense-finder.pasteur.cloud/wiki/defense-systems/avs).
+
+## Molecular mechanisms
+
+As far as we are aware, the molecular mechanism is unknown. However, the molecular mechanism of closely related systems was previously studied. See bNACHT (https://defense-finder.pasteur.cloud/wiki/defense-systems/nlr), CARD_NLR (https://defense-finder.pasteur.cloud/wiki/defense-systems/card_nlr) and Avs (AVAST) (https://defense-finder.pasteur.cloud/wiki/defense-systems/avs)
+
## Example of genomic structure
The Rst_TIR-NLR system is composed of one protein: TIR.
@@ -73,13 +88,3 @@ end
style Title3 fill:none,stroke:none,stroke-width:none
style Title4 fill:none,stroke:none,stroke-width:none
</mermaid>
-## Relevant abstracts
-
-::relevant-abstracts
----
-items:
- - doi: 10.1016/j.chom.2022.02.018
-
----
-::
-
--
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