From 065da199ddf1525d3661a05ecaef404f146c5bb0 Mon Sep 17 00:00:00 2001
From: Remi  PLANEL <rplanel@pasteur.fr>
Date: Tue, 19 Dec 2023 18:30:25 +0100
Subject: [PATCH] fix typo

---
 .../{Defense systems effectors => defense-systems-effectors.md} | 0
 content/3.defense-systems/detocs.md                             | 2 +-
 2 files changed, 1 insertion(+), 1 deletion(-)
 rename content/2.general-concepts/{Defense systems effectors => defense-systems-effectors.md} (100%)

diff --git a/content/2.general-concepts/Defense systems effectors b/content/2.general-concepts/defense-systems-effectors.md
similarity index 100%
rename from content/2.general-concepts/Defense systems effectors
rename to content/2.general-concepts/defense-systems-effectors.md
diff --git a/content/3.defense-systems/detocs.md b/content/3.defense-systems/detocs.md
index 72039702..5a9a42d3 100644
--- a/content/3.defense-systems/detocs.md
+++ b/content/3.defense-systems/detocs.md
@@ -8,7 +8,7 @@ tableColumns:
         During viral infection, cells can deploy immune strategies that deprive viruses of molecules essential for their replication. Here, we report a family of immune effectors in bacteria that, upon phage infection, degrade cellular adenosine triphosphate (ATP) and deoxyadenosine triphosphate (dATP) by cleaving the N-glycosidic bond between the adenine and sugar moieties. These ATP nucleosidase effectors are widely distributed within multiple bacterial defense systems, including cyclic oligonucleotide-based antiviral signaling systems (CBASS), prokaryotic argonautes, and nucleotide-binding leucine-rich repeat (NLR)-like proteins, and we show that ATP and dATP degradation during infection halts phage propagation. By analyzing homologs of the immune ATP nucleosidase domain, we discover and characterize Detocs, a family of bacterial defense systems with a two-component phosphotransfer-signaling architecture. The immune ATP nucleosidase domain is also encoded within diverse eukaryotic proteins with immune-like architectures, and we show biochemically that eukaryotic homologs preserve the ATP nucleosidase activity. Our findings suggest that ATP and dATP degradation is a cell-autonomous innate immune strategy conserved across the tree of life.
     Sensor: Unknown
     Activator: Unknown
-    Effector:Nucleotide modifying
+    Effector: Nucleotide modifying
     PFAM: PF01048, PF18742
 contributors: 
     - FranÃ§ois Rousset
-- 
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