From 1cd21656b0a0973bc26348f58c664d43d93051af Mon Sep 17 00:00:00 2001
From: ftesson <florian.tesson@cri-paris.org>
Date: Tue, 9 Jan 2024 16:53:42 +0100
Subject: [PATCH] Update abiz.md
---
content/3.defense-systems/abiz.md | 28 +++++++++++++++++++---------
1 file changed, 19 insertions(+), 9 deletions(-)
diff --git a/content/3.defense-systems/abiz.md b/content/3.defense-systems/abiz.md
index 5bfcd31d..cb817499 100644
--- a/content/3.defense-systems/abiz.md
+++ b/content/3.defense-systems/abiz.md
@@ -9,9 +9,28 @@ tableColumns:
Sensor: Unknown
Activator: Unknown
Effector: Membrane disrupting
+contributors:
+ - Florian Tesson
+relevantAbstracts:
+ - doi: 10.1023/A:1002027321171
+ - doi: 10.1128/JB.00904-06
---
# AbiZ
+
+## Description
+
+AbiZ was discovered in 2006 on a *Lactococcus lactis* conjugative plasmid pTR2030 :ref{doi=10.1128/JB.00904-06}.
+
+AbiZ is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry :ref{doi=10.1016/j.mib.2005.06.006}. AbiZ is classified as abortive infection in :ref{doi=10.1016/j.mib.2023.102312}.
+
+AbiZ is composed of a single protein AbiZ.
+
+## Molecular mechanism
+
+AbiZ act as an abortive infection system. AbiZ proteins sense holins and lysins from the infecting bacteriophage and use them to induce
+premature cell lysis :ref{doi=10.1128/JB.00904-06,10.1146/annurev-virology-011620-040628}.
+
## Example of genomic structure
The AbiZ is composed of 1 protein: AbiZ.
@@ -77,13 +96,4 @@ end
style Title3 fill:none,stroke:none,stroke-width:none
style Title4 fill:none,stroke:none,stroke-width:none
</mermaid>
-## Relevant abstracts
-::relevant-abstracts
----
-items:
- - doi: 10.1023/A:1002027321171
- - doi: 10.1128/JB.00904-06
-
----
-::
--
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