From 31479d38ebd53fab7d343b6ef08a27108f27cf78 Mon Sep 17 00:00:00 2001
From: ftesson <florian.tesson@pasteur.fr>
Date: Tue, 23 Jan 2024 09:14:58 +0100
Subject: [PATCH] go back to NLR to stick with DefenseFinder output
---
content/3.defense-systems/nlr.md | 7 +++++--
1 file changed, 5 insertions(+), 2 deletions(-)
diff --git a/content/3.defense-systems/nlr.md b/content/3.defense-systems/nlr.md
index 48df3a21..d3175489 100644
--- a/content/3.defense-systems/nlr.md
+++ b/content/3.defense-systems/nlr.md
@@ -1,5 +1,5 @@
---
-title: bNacht
+title: NLR
layout: article
tableColumns:
article:
@@ -16,14 +16,17 @@ relevantAbstract:
- doi: 10.1016/j.cell.2023.04.015
---
-# bNacht
+# NLR / bNACHT
## Description
+This NLR like system is also known as the bNACHT systems.
+
Several proteins containing a NACHT module were found to have anti-phage activity. NACHT modules are also found in metazoans, where they play a role in innate immunity.
bNacht systems have some similarities with other defense systems:
[CARD_NLR](/defense-systems/card_nlr) , [Rst_TIR-NLR](/defense-systems/rst_tir-nlr), [Avs](/defense-systems/avs).
## Molecular mechanism
+
Bacterial NACHT module-containing proteins (bNACHT) encompass a C-terminal sensor, a central NACHT module, and N-terminal effector modules. The N-terminal effectors associated with bNACHT proteins are diverse, and include domains that have been previously described to be involved in other defense systems {doi=10.1016/j.cell.2023.04.015}
As far as we are aware, the precise molecular mechanism of bNACHT is unknown.
--
GitLab