diff --git a/content/3.defense-systems/pd-t4-3.md b/content/3.defense-systems/pd-t4-3.md index 9a32464e94f0c934e0413dfe2d3b38630922a369..b97d71f954279bfda3cb8d8bccbe446afac5fb22 100644 --- a/content/3.defense-systems/pd-t4-3.md +++ b/content/3.defense-systems/pd-t4-3.md @@ -9,9 +9,22 @@ tableColumns: Sensor: Unknown Activator: Unknown Effector: Unknown +contributors: + - Ernest Mordret +relevant abstracts: + - doi: 10.1038/s41564-022-01219-4 --- # PD-T4-3 + +## Description + +PD-T4-3 is a single gene system isolated during an experimental screen of fosmids derived from 71 strains of diverse E.coli, and cloned back in a derivative of K12. Fragments containing the PD-T4-3 gene were shown to provide resistance to phage T4. The protein is characterized by a GIY-YIG nuclease domain, and mutations inactivating this domain abolished the resistance phenotype. It was originally found on a µ-like prophage + +## Molecular mechanism + +the molecular mechanism of this system is unknown + ## Example of genomic structure The PD-T4-3 system is composed of one protein: PD-T4-3. @@ -69,12 +82,5 @@ end style Title3 fill:none,stroke:none,stroke-width:none style Title4 fill:none,stroke:none,stroke-width:none </mermaid> -## Relevant abstracts - -::relevant-abstracts ---- -items: - - doi: 10.1038/s41564-022-01219-4 - --- ::