diff --git a/content/2.defense-systems/rst_paris.md b/content/2.defense-systems/paris.md similarity index 81% rename from content/2.defense-systems/rst_paris.md rename to content/2.defense-systems/paris.md index d8194bf596ef1dfe85391fdd9b468b2caf4bb411..8a1a858eaa94444626fb5f8d4069cf4d94598f32 100644 --- a/content/2.defense-systems/rst_paris.md +++ b/content/2.defense-systems/paris.md @@ -1,5 +1,5 @@ --- -title: Rst_PARIS +title: Paris tableColumns: article: doi: 10.1016/j.chom.2022.02.018 @@ -10,8 +10,8 @@ tableColumns: Effector: Unknown --- -# Rst_PARIS -# Rst_PARIS +# Paris +# Paris ## Description PARIS (for Phage Anti-Restriction-Induced System) is a novel anti-phage system. PARIS is found in 4% of prokaryotic genomes. It comprises an ATPase associated with a DUF4435 protein, which can be found either as a two-gene cassette or a single-gene fusion (1). @@ -20,39 +20,39 @@ This system relies on an unknown [Abortive infection](/general-concepts/abortive ## Example of genomic structure -The Rst_PARIS system have been describe in a total of 4 subsystems. +The Paris system have been describe in a total of 4 subsystems. Here is some example found in the RefSeq database: -{max-width=750px} +{max-width=750px} PARIS_I subsystem in the genome of *Salmonella enterica* (GCF_020715485.1) is composed of 2 proteins: AAA_15 (WP_001520831.1)and, DUF4435 (WP_010989064.1). -{max-width=750px} +{max-width=750px} PARIS_II subsystem in the genome of *Enterobacter cloacae* (GCF_023238665.1) is composed of 2 proteins: DUF4435 (WP_071830092.1)and, AAA_21 (WP_061772587.1). -{max-width=750px} +{max-width=750px} PARIS_II_merge subsystem in the genome of *Desulfovibrio desulfuricans* (GCF_017815575.1) is composed of 1 protein: AAA_21_DUF4435 (WP_209818471.1). -{max-width=750px} +{max-width=750px} PARIS_I_merge subsystem in the genome of *Sideroxydans lithotrophicus* (GCF_000025705.1) is composed of 1 protein: AAA_15_DUF4435 (WP_013030315.1). ## Distribution of the system among prokaryotes -The Rst_PARIS system is present in a total of 463 different species. +The Paris system is present in a total of 463 different species. Among the 22k complete genomes of RefSeq, this system is present in 1145 genomes (5.0 %). -{max-width=750px} +{max-width=750px} -*Proportion of genome encoding the Rst_PARIS system for the 14 phyla with more than 50 genomes in the RefSeq database.* *Pie chart of the repartition of all the subsystems found in the RefSeq database.* +*Proportion of genome encoding the Paris system for the 14 phyla with more than 50 genomes in the RefSeq database.* *Pie chart of the repartition of all the subsystems found in the RefSeq database.* ## Experimental validation -Rst_PARIS systems were experimentally validated using: +Paris systems were experimentally validated using: Subsystem Paris 1 with a system from *Escherichia coli (P4 loci)* in *Escherichia coli* has an anti-phage effect against Lambda, T4, CLB_P2, LF82_P8, Al505_P2, T7 (Rousset et al., 2022) diff --git a/public/rst_paris/Distribution_Rst_PARIS.svg b/public/paris/Distribution_Paris.svg similarity index 100% rename from public/rst_paris/Distribution_Rst_PARIS.svg rename to public/paris/Distribution_Paris.svg diff --git a/public/rst_paris/PARIS_I.svg b/public/paris/PARIS_I.svg similarity index 100% rename from public/rst_paris/PARIS_I.svg rename to public/paris/PARIS_I.svg diff --git a/public/rst_paris/PARIS_II.svg b/public/paris/PARIS_II.svg similarity index 100% rename from public/rst_paris/PARIS_II.svg rename to public/paris/PARIS_II.svg diff --git a/public/rst_paris/PARIS_II_merge.svg b/public/paris/PARIS_II_merge.svg similarity index 100% rename from public/rst_paris/PARIS_II_merge.svg rename to public/paris/PARIS_II_merge.svg diff --git a/public/rst_paris/PARIS_I_merge.svg b/public/paris/PARIS_I_merge.svg similarity index 100% rename from public/rst_paris/PARIS_I_merge.svg rename to public/paris/PARIS_I_merge.svg