From 5b4a365d6f19fd2011447db95cfb17c60d196d46 Mon Sep 17 00:00:00 2001
From: ftesson <florian.tesson@cri-paris.org>
Date: Tue, 16 Jan 2024 18:08:39 +0100
Subject: [PATCH] first version jukab

---
 content/3.defense-systems/jukab.md | 11 ++++++++++-
 1 file changed, 10 insertions(+), 1 deletion(-)

diff --git a/content/3.defense-systems/jukab.md b/content/3.defense-systems/jukab.md
index 61f8bb4e..1f6778e9 100644
--- a/content/3.defense-systems/jukab.md
+++ b/content/3.defense-systems/jukab.md
@@ -13,7 +13,16 @@ relevantAbstracts:
 
 # JukAB
 
-## To do 
+## Description
+JukAB was shown to be active against nucleus-like forming Jumbo phages :ref{doi=10.1038/s41586-022-05013-4} in *Pseudomonas aeruginosa* :ref{doi=10.1101/2022.09.17.508391}. This system was named JukAB for **Ju**mbo phage **K*iller.
+
+JukAB is composed of two protein JukA and JukB. JukA encode for the DUF3944 domain present in other potential defense system according to :ref{doi=10.1101/2022.09.17.508391}.
+
+## Molecular mechanism
+
+JukAB is acting at the early stage of PhiKZ infection before the phage forms its nucleus.
+
+Using fluorescence microscopy, the authors showed that JukA is acting as a sensor of the phage infection using PhiKZ ejection factors :ref{doi=10.1101/2022.09.17.508391}. After the detection of the infection by JukA, JukB is recruted and the phage 
 
 ## Example of genomic structure
 
-- 
GitLab