diff --git a/content/3.defense-systems/rst_gop_beta_cll.md b/content/3.defense-systems/rst_gop_beta_cll.md index 1d287bb43a7dacff67ba37c7669694729d288c9c..c64bf28bc32129ef5cb9a69ff06031f497a7bc3f 100644 --- a/content/3.defense-systems/rst_gop_beta_cll.md +++ b/content/3.defense-systems/rst_gop_beta_cll.md @@ -10,11 +10,29 @@ tableColumns: Activator: Unknown Effector: Unknown PFAM: PF14350 +contributors: + - Florian Tesson relevantAbstracts: - doi: 10.1016/j.chom.2022.02.018 --- # Rst_gop_beta_cll + +## Description + +The gop-beta-cll system was shown to have an antiphage activity in 2022 :ref{doi=10.1016/j.chom.2022.02.018} against Escherichia coli phage lambda and P1. + +The gop-beta-cll was first described as a nonessential region of the bacteriophage P4 :ref{doi=10.1128/jvi.64.1.24-36.1990}. + +This system is composed of 3 genes: gop, beta and cll. + +## Molecular mechanism + +As far as we are aware, the molecular mechanism is unknown. + +The production of the gop protein without beta is toxic :ref{doi=10.1128/jvi.64.1.24-36.1990} suggesting a toxin antitoxin mechanism :ref{doi=10.1016/j.chom.2022.02.018}. + + ## Example of genomic structure The Rst_gop_beta_cll is composed of 3 proteins: beta, cll and gop.