From 671cc2b0f75bff4bb1a4747ab0d7b490f8243a17 Mon Sep 17 00:00:00 2001
From: Lucas PAOLI <lucas.paoli@pasteur.fr>
Date: Wed, 22 Nov 2023 14:57:05 +0100
Subject: [PATCH] Update paris.md according to Hackaton guidelines, see
 https://gitlab.pasteur.fr/mdm-lab/wiki/-/issues/230

---
 content/3.defense-systems/paris.md | 18 +++++++-----------
 1 file changed, 7 insertions(+), 11 deletions(-)

diff --git a/content/3.defense-systems/paris.md b/content/3.defense-systems/paris.md
index 4a08c649..d3badc5b 100644
--- a/content/3.defense-systems/paris.md
+++ b/content/3.defense-systems/paris.md
@@ -9,13 +9,19 @@ tableColumns:
     Sensor: Sensing of phage protein
     Activator: Unknown
     Effector: Unknown
+contributors: 
+  - Lucas Paoli
+relevantAbstracts:
+  - doi: 10.1016/j.chom.2022.02.018
 ---
 
 # Paris
 
 ## Description
 
-PARIS (for Phage Anti-Restriction-Induced System) is a novel anti-phage system. PARIS is found in 4% of prokaryotic genomes. It comprises an ATPase associated with a DUF4435 protein, which can be found either as a two-gene cassette or a single-gene fusion (1).
+PARIS (for Phage Anti-Restriction-Induced System) is a novel anti-phage system. It comprises an ATPase associated with a DUF4435 protein, which can be found either as a two-gene cassette or a single-gene fusion (1).
+
+## Molecular mechanisms
 
 This system relies on an unknown [Abortive infection](/general-concepts/abortive-infection) mechanism to trigger growth arrest upon sensing a phage-encoded protein (Ocr). Interestingly, the Ocr protein has been found to inhibit R-M systems and BREX systems, making PARIS a suitable defense mechanism against RM resistant and/or BREX resistant phages (1, 2, 3). 
 
@@ -145,13 +151,3 @@ end
     style Title3 fill:none,stroke:none,stroke-width:none
     style Title4 fill:none,stroke:none,stroke-width:none
 </mermaid>
-## Relevant abstracts
-
-::relevant-abstracts
----
-items:
-    - doi: 10.1016/j.chom.2022.02.018
-
-
----
-::
-- 
GitLab