diff --git a/content/3.defense-systems/gabija.md b/content/3.defense-systems/gabija.md index 65b3b8ab21fc68c27ce89f402ceab77cfc45c167..5c18050cbb47378f9f096e1626fee426e6f1b219 100644 --- a/content/3.defense-systems/gabija.md +++ b/content/3.defense-systems/gabija.md @@ -16,15 +16,15 @@ relevantAbstracts: - doi: 10.1093/nar/gkab277 - doi: 10.1126/science.aar4120 - doi: 10.1016/j.chom.2023.06.014 - - doi: 10.1101/2023.05.01.538945 - - doi: 10.1101/2023.05.01.538930 + - doi: 10.1038/s41586-023-06855-2 + - doi: 10.1038/s41586-023-06869-w --- # Gabija ## Description -Gabija is named after the Lithuanian spirit of fire, protector of home and family. It is a two gene defense system found in 8.5% of the 4360 bacterial and archeal genomes that were initially analyzed :ref{doi=10.1126/science.aar4120}. Both proteins are necessary for defense and are forming a heteromeric octamer complex: GajA forms a central tetramer surrounded by two GajB dimers :ref{doi=10.1101/2023.05.01.538945,10.1093/nar/gkad951}. A phage protein inhibiting Gabija function was described, Gabidja anti defense 1 (Gad1) :ref{doi=10.1101/2023.05.01.538945,10.1101/2023.05.01.538930}. +Gabija is named after the Lithuanian spirit of fire, protector of home and family. It is a two gene defense system found in 8.5% of the 4360 bacterial and archeal genomes that were initially analyzed in :ref{doi=10.1126/science.aar4120}. Both proteins are necessary for defense and are forming a heteromeric octamer complex: GajA forms a central tetramer surrounded by two GajB dimers :ref{doi=10.1038/s41586-023-06855-2,10.1093/nar/gkad951}. A phage protein inhibiting Gabija function was described, Gabidja anti defense 1 (Gad1) :ref{doi=10.1038/s41586-023-06855-2,10.1038/s41586-023-06869-w}. ## Molecular mechanism