diff --git a/content/3.defense-systems/abia.md b/content/3.defense-systems/abia.md index 767f5802c40c02fed2e194be8e3acda25c70c482..a0b1d18ebd488262113100d596442efe543b1ab0 100644 --- a/content/3.defense-systems/abia.md +++ b/content/3.defense-systems/abia.md @@ -17,7 +17,19 @@ relevantAbstracts: --- # AbiA +The AbiA defense system was discovered in 1990 in a lactococcal plasmid :ref{doi=10.1128/aem.56.7.2255-2258.1990}. +AbiA is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry :ref{doi=10.1016/j.mib.2005.06.006}. AbiA is classified as possible abortive infection in :ref{doi=10.1016/j.mib.2023.102312}. + +Since it was discovered a similarity in amino acids was found with [AbiK](/defense-systems/abik). + +However, with the discovery of dozens of new systems, it was categorize as one of the UG/Abi defense systems :ref{doi=10.1093/nar/gkac467} along with [DRT](/defense-systems/drt) different subsystems, [Abik](/defense-systems/abik), [AbiP2](/defense-systems/abip2) and [Rst_RT_Nitralase_TM](/defense-systems/rst_rt-nitrilase-tm). + +Those systems are characterized by the presence of a reverse transcriptase domain of the "Unknown Group RT". + +## Molecular mechanism + +To our knowledge, the molecular mechanism is unknown. Similarly, for the other systems of this family, the molecular mechanism remain unknown. ## Example of genomic structure