From 813ca6eb17d6a6224ee01e07d9af9d7d681b861c Mon Sep 17 00:00:00 2001
From: ftesson <florian.tesson@pasteur.fr>
Date: Mon, 22 Jan 2024 16:53:12 +0100
Subject: [PATCH] add information on abia
---
content/3.defense-systems/abia.md | 15 +++++++++++++++
1 file changed, 15 insertions(+)
diff --git a/content/3.defense-systems/abia.md b/content/3.defense-systems/abia.md
index 7159f29a..02eafd5e 100644
--- a/content/3.defense-systems/abia.md
+++ b/content/3.defense-systems/abia.md
@@ -10,6 +10,8 @@ tableColumns:
Activator: Unknown
Effector: Unknown
PFAM: PF00078, PF18160, PF18732
+contributors:
+ - Florian Tesson
relevantAbstracts:
- doi: 10.1023/A:1002027321171
- doi: 10.1016/j.mib.2005.06.006
@@ -17,6 +19,19 @@ relevantAbstracts:
---
# AbiA
+The AbiA defense system was discovered in 1990 in a lactococcal plasmid :ref{doi=10.1128/aem.56.7.2255-2258.1990}.
+
+AbiA is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry :ref{doi=10.1016/j.mib.2005.06.006}. AbiA is classified as a possible abortive infection in :ref{doi=10.1016/j.mib.2023.102312}.
+
+Since it was discovered a similarity in amino acids was found with [AbiK](/defense-systems/abik).
+
+However, with the discovery of dozens of new systems, it was categorized as one of the UG/Abi defense systems :ref{doi=10.1093/nar/gkac467} along with [DRT](/defense-systems/drt) different subsystems, [Abik](/defense-systems/abik), [AbiP2](/defense-systems/abip2) and [Rst_RT_Nitralase_TM](/defense-systems/rst_rt-nitrilase-tm).
+
+Those systems are characterized by the presence of a reverse transcriptase domain of the "Unknown Group RT".
+
+## Molecular mechanism
+
+To our knowledge, the molecular mechanism is unknown. Similarly, for the other systems of this family, the molecular mechanism remains unknown.
## Example of genomic structure
--
GitLab