From 82e0b30678548dc4d4bd9a1da432dc5f53dbd7ce Mon Sep 17 00:00:00 2001
From: ftesson <florian.tesson@cri-paris.org>
Date: Wed, 3 Jan 2024 12:26:56 +0100
Subject: [PATCH] Update septu.md
---
content/3.defense-systems/septu.md | 30 +++++++++++++++++++-----------
1 file changed, 19 insertions(+), 11 deletions(-)
diff --git a/content/3.defense-systems/septu.md b/content/3.defense-systems/septu.md
index 7277766d..d5291d40 100644
--- a/content/3.defense-systems/septu.md
+++ b/content/3.defense-systems/septu.md
@@ -10,9 +10,27 @@ tableColumns:
Activator: Unknown
Effector: Unknown
PFAM: PF13175, PF13304, PF13476
+contributors:
+ - Florian Tesson
+relevantAbstracts:
+ - doi: 10.1016/j.cell.2020.09.065
+ - doi: 10.1093/nar/gkab883
+ - doi: 10.1126/science.aar4120
---
-
# Septu
+
+## Description
+The Septu defense system was discovered in 2018 in *Bacillus* :ref{doi=10.1126/science.aar4120}. The name of the system is related to Septu (or Sopdu) the ancient egypt god of the sky and of eastern border regions.
+
+The Septu defense systems is composed of two protein PtuA and PtuB: PtuA encoding for an ATPase (AAA15/AAA21) and PtuB with HNH endonuclease domain.
+
+After the discovery of Septu, two studies discovered separatly another form of Septu :ref{doi=10.1093/nar/gkab883,10.1016/j.cell.2020.09.065}. This new subtype encode a thrid protein with a reverse transcriptase domain. This system is either reffer as Septu Type II :ref{doi=10.1093/nar/gkab883} or as [Retron](/defense-systems/retron) subtype RT-I-A :ref{doi=10.1016/j.cell.2020.09.065,10.1016/j.cell.2020.09.065}.
+
+The Septu defense system is part of large category of system that encode the AAA15/21 ABC ATPase :ref{doi=10.1111/mmi.15074}.
+
+## Molecular mechanism
+As far as we are aware, the molecular mechanism is unknown.
+
## Example of genomic structure
The Septu is composed of 2 proteins: PtuA and PtuB.
@@ -101,15 +119,5 @@ end
style Title3 fill:none,stroke:none,stroke-width:none
style Title4 fill:none,stroke:none,stroke-width:none
</mermaid>
-## Relevant abstracts
-
-::relevant-abstracts
----
-items:
- - doi: 10.1016/j.cell.2020.09.065
- - doi: 10.1093/nar/gkab883
- - doi: 10.1126/science.aar4120
----
-::
--
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