From 84c97219e1fb7e5913e7270670f1b88c4d07e2f7 Mon Sep 17 00:00:00 2001
From: ftesson <florian.tesson@pasteur.fr>
Date: Mon, 22 Jan 2024 16:38:26 +0100
Subject: [PATCH] add information on abiz.md
---
content/3.defense-systems/abiz.md | 14 ++++++++++++++
1 file changed, 14 insertions(+)
diff --git a/content/3.defense-systems/abiz.md b/content/3.defense-systems/abiz.md
index 50555aa0..a17cdf90 100644
--- a/content/3.defense-systems/abiz.md
+++ b/content/3.defense-systems/abiz.md
@@ -9,12 +9,26 @@ tableColumns:
Sensor: Unknown
Activator: Unknown
Effector: Membrane disrupting
+contributors:
+ - Florian Tesson
relevantAbstracts:
- doi: 10.1023/A:1002027321171
- doi: 10.1128/JB.00904-06
---
# AbiZ
+
+## Description
+
+AbiZ was discovered in 2006 on a *Lactococcus lactis* conjugative plasmid pTR2030 :ref{doi=10.1128/JB.00904-06}.
+
+AbiZ is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry :ref{doi=10.1016/j.mib.2005.06.006}. AbiZ is classified as abortive infection in :ref{doi=10.1016/j.mib.2023.102312}.
+
+AbiZ is composed of a single protein AbiZ.
+
+## Molecular mechanism
+AbiZ acts as an abortive infection system. AbiZ proteins sense holins and lysins from the infecting bacteriophage and use them to induce premature cell lysis :ref{doi=10.1128/JB.00904-06,10.1146/annurev-virology-011620-040628}.
+
## Example of genomic structure
The AbiZ is composed of 1 protein: AbiZ.
--
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