diff --git a/content/3.defense-systems/gabija.md b/content/3.defense-systems/gabija.md index 9af5358281bb4d757965f06264fa0f8b79752667..7327868ee424e9e020bbca6b701dc9da3c5f604a 100644 --- a/content/3.defense-systems/gabija.md +++ b/content/3.defense-systems/gabija.md @@ -11,16 +11,17 @@ tableColumns: Effector: Degrading nucleic acids PFAM: PF00580, PF11398, PF13175, PF13245, PF13304, PF13361, PF13476 contributors: - -Nathalie Bechon + - Nathalie Bechon relevantAbstracts: - - doi: 10.1093/nar/gkab277 - - doi: 10.1126/science.aar4120 - - doi: 10.1016/j.chom.2023.06.014 - - doi: 10.1101/2023.05.01.538945 - - doi: 10.1101/2023.05.01.538930 + - doi: 10.1093/nar/gkab277 + - doi: 10.1126/science.aar4120 + - doi: 10.1016/j.chom.2023.06.014 + - doi: 10.1101/2023.05.01.538945 + - doi: 10.1101/2023.05.01.538930 --- # Gabija + ## Description Gabija is named after the Lithuanian spirit of fire, protector of home and family. It is a two gene defense system found in 8.5% of the 4360 bacterial and archeal genomes that were initially analyzed (:ref{doi=10.1126/science.aar4120}). Both proteins are necessary for defense and are forming a heteromeric octamer complex: GajA forms a central tetramer surrounded by two GajB dimers (ref:{doi=10.1101/2023.05.01.538945, 10.1093/nar/gkad951}). A phage protein inhibiting Gabija function was described, Gabidja anti defense 1 (Gad1)(:ref{doi=10.1101/2023.05.01.538945,10.1101/2023.05.01.538930}).