diff --git a/content/3.defense-systems/pd-t7-5.md b/content/3.defense-systems/pd-t7-5.md index 1b97e8c5508038ee94db612f28f61b1974956453..7d2dbf89ce09f87321cba8e7153586abf9fc7486 100644 --- a/content/3.defense-systems/pd-t7-5.md +++ b/content/3.defense-systems/pd-t7-5.md @@ -9,14 +9,22 @@ tableColumns: Sensor: Unknown Activator: Unknown Effector: Unknown +contributors: + - Hugo Vaysset relevantAbstracts: - - doi: 10.1038/s41564-022-01219-4 + - doi: 10.1038/s41564-022-01219-4 --- # PD-T7-5 -## Example of genomic structure -The PD-T7-5 is composed of 1 protein: PD-T7-5. +## Description +PD-T7-5 is a defense system composed of a single protein which was discovered in :ref{doi=10.1038/s41564-022-01219-4}. Its antiphage activity was assessed by heterologous expression in *E. coli* against T7 and to reduce the size of lysis plaques of T3 :ref{doi=10.1038/s41564-022-01219-4}. PD-T7-5 contains a PD(D/E)XK nuclease domain like [PD-T7-1](/defense-systems/pd-t7-1). + +## Molecular mechanism +As far as we are aware, the molecular mechanism is unknown. However, the presence of a PD(D/E)XK domain in PD-T7-5 suggests a mechanism of action via DNA degradation :ref{doi=10.1038/s41564-022-01219-4}. + +## Example of genomic structure +The PD-T7-5 system is composed of one protein: PD-T7-5. Here is an example found in the RefSeq database: @@ -76,4 +84,3 @@ end style Title3 fill:none,stroke:none,stroke-width:none style Title4 fill:none,stroke:none,stroke-width:none </mermaid> -