diff --git a/content/3.defense-systems/pd-t4-4.md b/content/3.defense-systems/pd-t4-4.md index 21c35ecf5417359d2b0cddf0dd4287459635c7c5..8eb17137f0068cf1d5e42dc98a7c90e1d9d98387 100644 --- a/content/3.defense-systems/pd-t4-4.md +++ b/content/3.defense-systems/pd-t4-4.md @@ -10,9 +10,19 @@ tableColumns: Activator: Unknown Effector: Unknown PFAM: PF13175, PF13304 +contributors: + - Nathalie Bechon +relevantAbstracts + - doi: 10.1038/s41564-022-01219-4 --- # PD-T4-4 +## Description +PD-T4-4 is a defense system composed of two proteins, a P-loop NTPase and a nuclease, that is most likely protecting the bacterial population through abortive infection. It was identified from an ICE in an *E. coli* genome. + +## Molecular mechanisms +PD-T4-4 molecular mechanism is currently unknown, although it is most likely an abortive infection system. + ## Example of genomic structure The PD-T4-4 system is composed of 2 proteins: PD-T4-4_A and, PD-T4-4_B. @@ -21,7 +31,7 @@ Here is an example found in the RefSeq database: {max-width=750px} -PD-T4-4 system in the genome of *Escherichia coli* (GCF_013376895.1) is composed of 2 proteins: PD-T4-4_B (WP_176670803.1)and, PD-T4-4_A (WP_027920142.1). +PD-T4-4 system in the genome of *Escherichia coli* (GCF_013376895.1) is composed of 2 proteins: PD-T4-4_B (WP_176670803.1) and, PD-T4-4_A (WP_027920142.1). ## Distribution of the system among prokaryotes @@ -78,13 +88,4 @@ end style Title3 fill:none,stroke:none,stroke-width:none style Title4 fill:none,stroke:none,stroke-width:none </mermaid> -## Relevant abstracts - -::relevant-abstracts ---- -items: - - doi: 10.1038/s41564-022-01219-4 - ---- -::