diff --git a/content/3.defense-systems/eleos.md b/content/3.defense-systems/eleos.md index 60836d57c049cb34d48fe6c53ed23324325269df..619bd3f24fc418460471268c5c2138015f01b664 100644 --- a/content/3.defense-systems/eleos.md +++ b/content/3.defense-systems/eleos.md @@ -10,23 +10,18 @@ tableColumns: Activator: Unknown Effector: Unknown PFAM: PF00350, PF01926, PF18709 - contributors: - - Alba Herrero del Valle -## Relevant abstracts - -::relevant-abstracts ---- -items: + - Alba Herrero del Valle +relevantAbstracts: - doi: 10.1016/j.chom.2022.09.017 - doi: 10.1101/2022.12.12.520048 --- ---- # Eleos ## Description -The Eleos (for the greek goddess of mercy) system was previously described as the Dynamins-like system in by Millman et al. :ref{doi=10.1016/j.chom.2022.09.017}. It is formed by the LeoA and LeoBC proteins. LeoBC has been found to be analogous to GIMAPs (GTPases immunity-associated proteins), that are interferon inducible :ref{doi=10.1101/2022.12.12.520048}. LeoA in *E. coli* ETEC H10407 localises to the periplasm and has been suggested to potientiate bacterial virulence. Its crystal structure has been solved :ref{doi=10.1371/journal.pone.0107211}. Eleos from *Bacillus vietnamensis* NBRC 101237 has been found to protect against jumbo-phages in *Bacillus subtilis* :ref{doi=10.1016/j.chom.2022.09.017}. +The Eleos (for the greek goddess of mercy) system was previously described as the Dynamins-like system in :ref{doi=10.1016/j.chom.2022.09.017}. It is formed by the LeoA and LeoBC proteins. LeoBC has been found to be analogous to GIMAPs (GTPases immunity-associated proteins), that are interferon inducible :ref{doi=10.1101/2022.12.12.520048}. LeoA in *E. coli* ETEC H10407 localises to the periplasm and has been suggested to potientiate bacterial virulence. Its crystal structure has been solved :ref{doi=10.1371/journal.pone.0107211}. Eleos from *Bacillus vietnamensis* NBRC 101237 has been found to protect against jumbo-phages in *Bacillus subtilis* :ref{doi=10.1016/j.chom.2022.09.017}. + ## Molecular mechanism As far as we are aware, the molecular mechanism is unknown.