From c1d095a93342ec4232efab5a1d44b157054b5ec4 Mon Sep 17 00:00:00 2001 From: ftesson <florian.tesson@cri-paris.org> Date: Wed, 3 Jan 2024 11:49:19 +0100 Subject: [PATCH] Update abik.md --- content/3.defense-systems/abik.md | 35 ++++++++++++++++++++----------- 1 file changed, 23 insertions(+), 12 deletions(-) diff --git a/content/3.defense-systems/abik.md b/content/3.defense-systems/abik.md index 284f5d9d..2c91e310 100644 --- a/content/3.defense-systems/abik.md +++ b/content/3.defense-systems/abik.md @@ -10,9 +10,32 @@ tableColumns: Activator: Unknown Effector: Unknown PFAM: PF00078 +contributors: + - Florian Tesson +relevantAbstracts: + - doi: 10.1023/A:1002027321171 + - doi: 10.1016/j.mib.2005.06.006 + - doi: 10.1093/nar/gkac467 + - doi: 10.1128/aem.63.4.1274-1283.1997 --- # AbiK + +## Description + + +The AbiK defense system was discovered in 1997 in *Lactococcus lactis* :ref{doi=10.1128/aem.63.4.1274-1283.1997}. AbiK is a single gene system with a size of around 650 amino acid. + +AbiK is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry :ref{doi=10.1016/j.mib.2005.06.006}. + +Since it was discovered a similarity in amino acids was found with [AbiA](/defense-systems/abia). +However, with the discovery of dozens of new systems, it was categorize as one of the UG/Abi defense systems :ref{doi=10.1093/nar/gkac467} along with [DRT](/defense-systems/drt) different subsystems, [AbiA](/defense-systems/abia) and [AbiP2](/defense-systems/abip2). + +Those systems are characterized by the presence of a reverse transcriptase domain of the "Unknown Group RT". + +## Molecular mechanism +To our knowledge, the molecular mechanism is unknown. Similarly, for the other systems of this family, the molecular mechanism remain unknown. + ## Example of genomic structure The AbiK is composed of 1 protein: AbiK. @@ -71,15 +94,3 @@ end style Title3 fill:none,stroke:none,stroke-width:none style Title4 fill:none,stroke:none,stroke-width:none </mermaid> -## Relevant abstracts - -::relevant-abstracts ---- -items: - - doi: 10.1023/A:1002027321171 - - doi: 10.1016/j.mib.2005.06.006 - - doi: 10.1093/nar/gkac467 - ---- -:: - -- GitLab