diff --git a/content/3.defense-systems/abiz.md b/content/3.defense-systems/abiz.md index 50555aa04b01ae7607be5a2c4f4a760ccfd211c3..a17cdf9013dc657f533e380424736b90f6a2c871 100644 --- a/content/3.defense-systems/abiz.md +++ b/content/3.defense-systems/abiz.md @@ -9,12 +9,26 @@ tableColumns: Sensor: Unknown Activator: Unknown Effector: Membrane disrupting +contributors: + - Florian Tesson relevantAbstracts: - doi: 10.1023/A:1002027321171 - doi: 10.1128/JB.00904-06 --- # AbiZ + +## Description + +AbiZ was discovered in 2006 on a *Lactococcus lactis* conjugative plasmid pTR2030 :ref{doi=10.1128/JB.00904-06}. + +AbiZ is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry :ref{doi=10.1016/j.mib.2005.06.006}. AbiZ is classified as abortive infection in :ref{doi=10.1016/j.mib.2023.102312}. + +AbiZ is composed of a single protein AbiZ. + +## Molecular mechanism +AbiZ acts as an abortive infection system. AbiZ proteins sense holins and lysins from the infecting bacteriophage and use them to induce premature cell lysis :ref{doi=10.1128/JB.00904-06,10.1146/annurev-virology-011620-040628}. + ## Example of genomic structure The AbiZ is composed of 1 protein: AbiZ.