diff --git a/content/3.defense-systems/psyrta.md b/content/3.defense-systems/psyrta.md index 8c6cd412c758ab6e171948e15d101dedd91a95b9..b8fc01fa3574dd889d887394a782c166f42f3315 100644 --- a/content/3.defense-systems/psyrta.md +++ b/content/3.defense-systems/psyrta.md @@ -26,18 +26,23 @@ Originally found in a high throughput shotgun cloning of bacterial fragments in ## Molecular mechanisms -from :ref{doi=10.1016/j.molcel.2013.02.002} "The psyrT shares homology with domains of the RecQ helicase, -a family of proteins implicated in DNA repair (Bernstein et al., -2010); and the antitoxin of the same system, psyrA, has a nucle- -otide binding domain (COG0758) that was previously described -in proteins involved in DNA uptake" - -from :ref{10.1016/j.chom.2022.09.017} "Both systems encode an antitoxin -with homology to DprA, a single-stranded DNA (ssDNA)-binding -protein known to be involved in DNA transformation (Mortier- -Barrie` re et al., 2007). The toxin contains a phosphoribosyl trans- -ferase (PRTase) domain, which was previously found in effectors -of retron abortive infection systems " +from :ref{doi=10.1016/j.molcel.2013.02.002} : + +> The psyrT shares homology with domains of the RecQ helicase, +> a family of proteins implicated in DNA repair (Bernstein et al., +> 2010); and the antitoxin of the same system, psyrA, has a nucle- +> otide binding domain (COG0758) that was previously described +> in proteins involved in DNA uptake + + +from :ref{10.1016/j.chom.2022.09.017} : + +> Both systems encode an antitoxin +> with homology to DprA, a single-stranded DNA (ssDNA)-binding +> protein known to be involved in DNA transformation (Mortier- +> Barrière et al., 2007). The toxin contains a phosphoribosyl trans- +> ferase (PRTase) domain, which was previously found in effectors +> of retron abortive infection systems " ## Example of genomic structure