diff --git a/content/3.defense-systems/fs_sma.md b/content/3.defense-systems/fs_sma.md index 554019b23ea398cb2f0f7562aafb21363ff84635..b3455b9718469f88832d9e42b7417c4a94dea4bf 100644 --- a/content/3.defense-systems/fs_sma.md +++ b/content/3.defense-systems/fs_sma.md @@ -10,17 +10,17 @@ tableColumns: contributors: - Héloïse Georjon relevantAbstracts: - - doi: 10.1016/j.cell.2022.07.014 + - doi: 10.1016/j.cell.2022.07.014 --- # SMA ## Description -SMA (single-protein MazF-like antiphage system) was identified in a phage-inducible chromosomal island (PICI) found in *Staphylococcus aureus* ref{doi=10.1016/j.cell.2022.07.014}. SMA was shown to inhibit phage infection and to inhibit the formation of new virions after prophage induction. +SMA (single-protein MazF-like antiphage system) was identified in a phage-inducible chromosomal island (PICI) found in *Staphylococcus aureus* :ref{doi=10.1016/j.cell.2022.07.014}. SMA was shown to inhibit phage infection and to inhibit the formation of new virions after prophage induction. ## Molecular mechanisms -The SMA protein comprises a domain analogous to MazF. MazF a protein that is normally part of the MazEF toxin-antitoxin systems, in which MazF is a toxic endoribonuclease that targets mRNA ref{10.1016/s1097-2765(03)00402-7}. +The SMA protein comprises a domain analogous to MazF. MazF a protein that is normally part of the MazEF toxin-antitoxin systems, in which MazF is a toxic endoribonuclease that targets mRNA :ref{doi=10.1016/s1097-2765(03)00402-7}. As far as we are aware, the precise molecular mechanism of SMA is unknown. ## Example of genomic structure