diff --git a/content/3.defense-systems/abik.md b/content/3.defense-systems/abik.md index 52e54fccc348f3702f36f1697435f401a85872fd..a47abe9c2cf0cc136f6d75cfbf0ed7fc72c8767a 100644 --- a/content/3.defense-systems/abik.md +++ b/content/3.defense-systems/abik.md @@ -10,13 +10,32 @@ tableColumns: Activator: Unknown Effector: Unknown PFAM: PF00078 +contributors: + - Florian Tesson relevantAbstracts: - - doi: 10.1023/A:1002027321171 - - doi: 10.1016/j.mib.2005.06.006 - - doi: 10.1093/nar/gkac467 + - doi: 10.1023/A:1002027321171 + - doi: 10.1016/j.mib.2005.06.006 + - doi: 10.1093/nar/gkac467 + - doi: 10.1128/aem.63.4.1274-1283.1997 --- # AbiK + +## Description + + +The AbiK defense system was discovered in 1997 in *Lactococcus lactis* :ref{doi=10.1128/aem.63.4.1274-1283.1997}. AbiK is a single gene system with a size of around 650 amino acids. + +AbiK is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry :ref{doi=10.1016/j.mib.2005.06.006}. AbiK is classified as abortive infection in :ref{doi=10.1016/j.mib.2023.102312}. + +Since it was discovered a similarity in amino acids was found with [AbiA](/defense-systems/abia). +However, with the discovery of dozens of new systems, it was categorized as one of the UG/Abi defense systems :ref{doi=10.1093/nar/gkac467} along with [DRT](/defense-systems/drt) different subsystems, [AbiA](/defense-systems/abia), [AbiP2](/defense-systems/abip2) and [Rst_RT_Nitralase_TM](/defense-systems/rst_rt-nitrilase-tm). + +Those systems are characterized by the presence of a reverse transcriptase domain of the "Unknown Group RT". + +## Molecular mechanism +To our knowledge, the molecular mechanism is unknown. Similarly, for the other systems of this family, the molecular mechanism remains unknown. + ## Example of genomic structure The AbiK is composed of 1 protein: AbiK.