diff --git a/.Rproj.user/shared/notebooks/paths b/.Rproj.user/shared/notebooks/paths index 033fd27363a6431dd5faaf16a0e102d6bf55ce6e..63b87f60b490fabe6fade435ffb96cbfd531e4c4 100644 --- a/.Rproj.user/shared/notebooks/paths +++ b/.Rproj.user/shared/notebooks/paths @@ -1,4 +1,5 @@ /home/marie/Documents/HB_CC011/F2/Geno/Maestro/F2_geno_estmap1.R="42B0AE06" +/home/marie/Documents/stuart/stuart_package/stuart/DESCRIPTION="55556B0B" /home/marie/Documents/stuart/stuart_package/stuart/R/mark_estmap.R="F759F000" /home/marie/Documents/stuart/stuart_package/stuart/README.Rmd="4E06E7DC" /home/marie/Documents/stuart/stuart_package/stuart/vignettes/stuart.Rmd="01396A37" diff --git a/article/article_figures.Rmd b/article/article_figures.Rmd index fd16965990203d0c0d5785c170c6a1b3f727f890..3274d5f361e5af45dbaa11ce4024bef0182cbc0a 100644 --- a/article/article_figures.Rmd +++ b/article/article_figures.Rmd @@ -115,7 +115,7 @@ tab2 <- mark_estmap(tab=tab2,map=stuart_newmap,annot=annot_mini) na_plot <- tab2 %>% mutate(prop_NA=n_NA/176) %>% ggplot(aes(x=prop_NA)) + geom_histogram() + scale_y_log10() + - theme_bw() + + theme_classic() + labs(title="Proportion of missing genotyped", x="Proportion of NA",y="Number of markers") + theme( @@ -138,6 +138,9 @@ prop_plot <- tab2 %>% filter(n_NA<88) %>% filter(!chr %in% c("M","X","Y")) %>% ggplot(aes(x=n_HM1/(n_HM1+n_HM2+n_HT),y=n_HM2/(n_HM1+n_HM2+n_HT),color=as.factor(exclude_prop))) + geom_point() + scale_color_manual(values=c("#66bd63","#b2182b"),labels = c("Retained", "Excluded")) + + geom_hline(yintercept = 0.1,linetype="dashed",size=.3) + + geom_vline(xintercept = 0.1,linetype="dashed",size=.3) + + geom_abline(intercept = 0.9, slope=-1,linetype="dashed",size=.3) + #geom_text(aes(label=ifelse(exclude_prop=="1",SNP.Name,'')),hjust=0, vjust=0,size=2) + labs(title="Exclusion of markers with mark_prop()", x="Proportion of homozygous individuals AA", @@ -148,14 +151,14 @@ prop_plot <- tab2 %>% filter(n_NA<88) %>% filter(!chr %in% c("M","X","Y")) %>% legend.position=c(0.8,0.8), legend.title = element_blank()) + theme(plot.title = element_text(hjust = 0.4,face="bold",size=14)) + - geom_segment(x = 0.2, y = 0.82, + geom_segment(x = 0.2, y = 0.78, xend = 0.25, yend = 0.72, color = "#1d91c0", - arrow = arrow(type="closed",length=unit(6,"points"))) + - geom_segment(x = 0.39, y = 0.62, + arrow = arrow(type="closed",length=unit(4,"points"))) + + geom_segment(x = 0.39, y = 0.58, xend = 0.44, yend = 0.52, color = "#1d91c0", - arrow = arrow(type="closed",length=unit(6,"points"))) + arrow = arrow(type="closed",length=unit(4,"points"))) prop_plot ``` ### Grid @@ -207,7 +210,7 @@ load("files/cluster/newmap_before.rda") # plot plotMap(cross_before,newmap_before,shift=TRUE) -plotmap_before <- ~plotMap(cross_before,newmap_before,shift=TRUE,main="Before stuart", ylab='^') +plotmap_before <- ~plotMap(cross_before,newmap_before,shift=TRUE,main="Before stuart", ylab='') ``` ### Before: plot genome scan @@ -247,10 +250,12 @@ pheno_before_plot pheno_before_zoom <- qtl_plot(pheno_before,lod=data.frame(group = c("alpha=0.05", "alpha=0.1","alpha=0.63"), lod = threshold_before[1:3]), ylab="LOD score", - title="QTL mapping", chrs = "13", size=0.6) + - theme(legend.position = "none") + + theme(legend.position = "none", + strip.background = element_blank(), + strip.text.x = element_blank()) + + xlab("Position (cM)") + ggtitle("") pheno_before_zoom ``` @@ -345,7 +350,8 @@ pheno_after_plot <- qtl_plot(pheno_after,lod=data.frame(group = c("alpha=0.05", ylab="LOD score", title="QTL mapping", x.label = element_blank(), - size=0.6) + + size=0.6, + strip.pos="bottom") + theme(legend.position = "none") + ggtitle("") pheno_after_plot diff --git a/article/figures/fig1.pdf b/article/figures/fig1.pdf index 7410150334a9146db76dcb8a985166ab137b3568..62d22743b5bc0f7ee0fa24e2524b6ab38afb31c9 100644 Binary files a/article/figures/fig1.pdf and b/article/figures/fig1.pdf differ diff --git a/article/figures/fig1.png b/article/figures/fig1.png new file mode 100644 index 0000000000000000000000000000000000000000..ff18e8950e721f07419d508926d1c6e522d5830a Binary files /dev/null and b/article/figures/fig1.png differ diff --git a/article/figures/fig2.pdf b/article/figures/fig2.pdf index 6ddf121a2969a25ed981cf57802b8eab0de4dc13..f63ee20b900bc04800ed7cee8ff78d3b015819e1 100644 Binary files a/article/figures/fig2.pdf and b/article/figures/fig2.pdf differ diff --git a/article/figures/fig2.png b/article/figures/fig2.png new file mode 100644 index 0000000000000000000000000000000000000000..49c49d40b5ea7d7d41efe40e8fac3698c08919f1 Binary files /dev/null and b/article/figures/fig2.png differ diff --git a/article/figures/fig3.pdf b/article/figures/fig3.pdf index 6c2322d6c3c8e60aab13926cacf8ed8640843fc3..d05b295cfd0afd7013a09b1b5ada286b07ba2c3d 100644 Binary files a/article/figures/fig3.pdf and b/article/figures/fig3.pdf differ diff --git a/article/figures/fig3.png b/article/figures/fig3.png new file mode 100644 index 0000000000000000000000000000000000000000..361116e45a362627221645596bdd631d402e4917 Binary files /dev/null and b/article/figures/fig3.png differ diff --git a/article/tables/tab_alleles.tex b/article/tables/tab_alleles.tex index a3b393a4572c90e815405f68c25c7e22d1c8e0b7..2bb108ae7e4773700e70e78f3058464a890c2dff 100644 --- a/article/tables/tab_alleles.tex +++ b/article/tables/tab_alleles.tex @@ -1,17 +1,17 @@ -% latex table generated in R 4.0.4 by xtable 1.8-4 package -% Tue Feb 15 09:50:40 2022 +% latex table generated in R 4.1.0 by xtable 1.8-4 package +% Thu Jun 9 11:29:15 2022 \begin{table}[ht] \centering -\begin{tabular}{lllll} +\begin{tabular}{llrr} \hline -marker & parent1 & parent2 & allele\_1 & allele\_2 \\ +Ind & Sex & Age & Pheno \\ \hline -S6J017555686 & C & C & T & C \\ - S6J113080150 & G & G & A & G \\ - gJAX00038569 & C & C & T & C \\ - mUNC21540855 & C & C & A & C \\ - gUNC21555204 & T & T & T & C \\ - gUNC21596600 & A & A & A & G \\ +201 & M & 7 & 10.53 \\ + 210 & M & 7 & 10.49 \\ + 308 & F & 7 & 10.97 \\ + 309 & M & 7 & 10.85 \\ + 310 & M & 7 & 11.07 \\ + 311 & F & 9 & 10.58 \\ \hline \end{tabular} \end{table}