diff --git a/article/.RData b/article/.RData
index e98699c949868b9ec4a46c57eb4ec9b233f0340e..7707416971adb9c17fd76c1962e608fcd5265f90 100644
Binary files a/article/.RData and b/article/.RData differ
diff --git a/article/article_figures.Rmd b/article/article_figures.Rmd
index f33b3457668b073084ee784808ee36e56efd34d3..d85762e7b32b476e89be10d9985790f24b46141c 100644
--- a/article/article_figures.Rmd
+++ b/article/article_figures.Rmd
@@ -289,21 +289,22 @@ colnames(peak5_tab) <- c("marker","chr","pos","allele\n1","allele\n2",
narrow_grid <- ggdraw() +
- draw_plot(pheno_before_annot_data2,.5,.8,.5,.16) +
- draw_plot(pheno_before_annot_data3,0,.64,.5,.16) +
- draw_plot(peak1,0,.48,.3,.16) +
- draw_plot(tableGrob(peak1_tab,rows=NULL),.3,.48,.7,.16) +
- draw_plot(peak3,0,.32,.3,.16) +
- draw_plot(tableGrob(peak3_tab,rows=NULL),.3,.32,.7,.16) +
- draw_plot(peak5,0,0,.3,.16) +
- draw_plot(tableGrob(peak5_tab,rows=NULL),.3,0,.7,.16) +
+ draw_plot(pheno_before_annot_data2,0,.75,.5,.25) +
+ draw_plot(pheno_before_annot_data3,.5,.75,.5,.25) +
+ draw_plot(peak1,0,.5,.3,.25) +
+ draw_plot(tableGrob(peak1_tab,rows=NULL),.3,.5,.7,.25) +
+ draw_plot(peak3,0,.25,.3,.25) +
+ draw_plot(tableGrob(peak3_tab,rows=NULL),.3,.25,.7,.25) +
+ draw_plot(peak5,0,0,.3,.25) +
+ draw_plot(tableGrob(peak5_tab,rows=NULL),.3,0,.7,.25) +
draw_plot_label(c("A","B","C","D","E","F","G","H"),
- c(0,.5,0,.5,0,.35,0,.35),c(.96,.96,.8,.8,.64,.615,.48,.45))
+ c(0,.5,0,.3,0,.3,.5,.7),c(1,1,.75,.75,.5,.5,.25,.25))
narrow_grid
-ggsave(narrow_grid,file="fig/figS3.pdf",width=10,height=17)
+ggsave(narrow_grid,file="figures/figS3.pdf",width=10,height=17)
+ggsave(narrow_grid,file="figures/figS3.png",width=10,height=17)
-rm(peak1,peak1_tab,peak2,peak2_tab,peak3,peak3_tab,peak4_tab,peak5,peak5_tab,peak6,peak6_tab,peak7,peak7_tab,peak11,peak11_tab)
+rm(peak1,peak1_tab,peak2,peak2_tab,peak3,peak3_tab,peak5,peak5_tab)
```
diff --git a/article/data1/.RData b/article/data1/.RData
index c4e56b79e9883cdcfb94d7e842772ad34f9b85c8..2960734e065e38ddfb0be96ebde9558528ef964c 100644
Binary files a/article/data1/.RData and b/article/data1/.RData differ
diff --git a/article/data1/data1.Rmd b/article/data1/data1.Rmd
index a3bb3d4696c7dc2de17d71274d764970da716b0d..3b6b6829f5a35ac02ebcce206d9bd43532c326f7 100644
--- a/article/data1/data1.Rmd
+++ b/article/data1/data1.Rmd
@@ -426,7 +426,7 @@ peak1 <- qtl_plot(pheno_before,lod=data.frame(group = c("alpha=0.05", "alpha=0.1
strip.text.x = element_blank()) +
xlab("Position (cM)") +
xlim(c(15,35)) +
- ggtitle("Peak 1")
+ ggtitle("Peak 1: 1 marker")
peak1
```
diff --git a/article/data1/data1.rda b/article/data1/data1.rda
index ce8e4bd07cfb88cf186c9dea318ed9cc1c8f344d..7b52e74023001f64b76dc04ca52f74224bacca23 100644
Binary files a/article/data1/data1.rda and b/article/data1/data1.rda differ
diff --git a/article/data2/.RData b/article/data2/.RData
index e45601ea57fb6bcbe5515d84cc4ab6999187da71..d96aa25a90287e3653ab4f547d42768f2e2872d5 100644
Binary files a/article/data2/.RData and b/article/data2/.RData differ
diff --git a/article/data2/data2.Rmd b/article/data2/data2.Rmd
index 4a04e28176c201fb3c6660777e9dbf4f2a195a84..a140a19931d26f6a5e0ae9ab7fbfc2671e12f52a 100644
--- a/article/data2/data2.Rmd
+++ b/article/data2/data2.Rmd
@@ -363,7 +363,8 @@ pheno_before_annot_data2 <- pheno_before_plot + geom_text(
y = lod,
label = label,
color="blue")
-)
+ ) +
+ ggtitle("Data 2")
pheno_before_annot_data2
rm(ann_dat_text)
@@ -388,7 +389,7 @@ peak3 <- qtl_plot(pheno_before,lod=data.frame(group = c("alpha=0.05", "alpha=0.1
strip.text.x = element_blank()) +
xlab("Position (cM)") +
xlim(c(11,31)) +
- ggtitle("Peak 3")
+ ggtitle("Peak 3: 1 pseudomarker")
peak3
```
@@ -448,6 +449,46 @@ pheno_data2 <- phenos %>% ggplot(aes(x=Pheno)) +
pheno_data2
```
+## Missing genotypes
+
+```{r}
+na_plot <- tab2 %>% mutate(prop_NA=n_NA/176) %>% ggplot(aes(x=prop_NA)) +
+ geom_histogram() +
+ scale_y_log10() +
+ theme_classic() +
+ labs(title="Proportion of missing genotyped",
+ x="Proportion of NA",y="Number of markers") +
+ theme(
+ aspect.ratio=0.8,
+ plot.title = element_text(hjust = 0.4,face="bold",size=14))
+
+na_plot
+```
+
+## Genotype proportions
+
+```{r}
+prop_plot <- tab2 %>% filter(n_NA<88) %>% filter(!chr %in% c("M","X","Y")) %>%
+ ggplot(aes(x=n_HM1/(n_HM1+n_HM2+n_HT),y=n_HM2/(n_HM1+n_HM2+n_HT),color=as.factor(exclude_prop))) +
+ geom_point() +
+ scale_color_manual(values=c("#66bd63","#b2182b"),labels = c("Retained", "Excluded")) +
+ geom_hline(yintercept = 0.1,linetype="dashed",size=.3) +
+ geom_vline(xintercept = 0.1,linetype="dashed",size=.3) +
+ geom_abline(intercept = 0.9, slope=-1,linetype="dashed",size=.3) +
+ labs(title="Exclusion of markers with mark_prop()",
+ x="Proportion of homozygous individuals AA",
+ y="Proportion of homozygous individuals BB",
+ color="Exclusion") +
+ theme_classic() +
+ theme(aspect.ratio=0.8,
+ legend.position=c(0.8,0.8),
+ legend.title = element_blank()) +
+ theme(plot.title = element_text(hjust = 0.4,face="bold",size=14))
+
+prop_plot
+```
+
+
```{r save_narrow}
tab2_data2 <- tab2
save(pheno_before_annot_data2,pheno_data2,peak3,peak3_tab,tab2_data2,
diff --git a/article/data2/data2.rda b/article/data2/data2.rda
index 71008b9bfc001c84249cf18ecfcdaca658f12d23..82298732fdfd63549aea0badd642c61a3a6f0759 100644
Binary files a/article/data2/data2.rda and b/article/data2/data2.rda differ
diff --git a/article/data3/.RData b/article/data3/.RData
index 7d39fc8ef76a1245bf928e72e768c13c9b9e0b49..5431637c11b1d396a7f99d780671978f859934f8 100644
Binary files a/article/data3/.RData and b/article/data3/.RData differ
diff --git a/article/data3/data3.Rmd b/article/data3/data3.Rmd
index 6f43e5a2efe3f01fadf7e642d84a697df59b74c6..96ba4038d11a5c8e95481df892448b88aa8fc237 100644
--- a/article/data3/data3.Rmd
+++ b/article/data3/data3.Rmd
@@ -373,7 +373,8 @@ pheno_before_annot_data3 <- pheno_before_plot + geom_text(
y = lod,
label = label,
color="blue")
-)
+ ) +
+ ggtitle("Data 3")
pheno_before_annot_data3
```
@@ -454,7 +455,7 @@ peak5 <- qtl_plot(pheno_before,lod=data.frame(group = c("alpha=0.05", "alpha=0.1
strip.text.x = element_blank()) +
xlab("Position (cM)") +
xlim(c(22,42)) +
- ggtitle("")
+ ggtitle("Peak 5: 1 marker and 1 pseudomarker")
peak5
```
@@ -509,6 +510,44 @@ pheno_data3 <- phenos %>% ggplot(aes(x=Pheno)) +
pheno_data3
```
+## Missing genotypes
+
+```{r}
+na_plot <- tab2 %>% mutate(prop_NA=n_NA/176) %>% ggplot(aes(x=prop_NA)) +
+ geom_histogram() +
+ scale_y_log10() +
+ theme_classic() +
+ labs(title="Proportion of missing genotyped",
+ x="Proportion of NA",y="Number of markers") +
+ theme(
+ aspect.ratio=0.8,
+ plot.title = element_text(hjust = 0.4,face="bold",size=14))
+
+na_plot
+```
+
+## Genotype proportions
+
+```{r}
+prop_plot <- tab2 %>% filter(n_NA<88) %>% filter(!chr %in% c("M","X","Y")) %>%
+ ggplot(aes(x=n_HM1/(n_HM1+n_HM2+n_HT),y=n_HM2/(n_HM1+n_HM2+n_HT),color=as.factor(exclude_prop))) +
+ geom_point() +
+ scale_color_manual(values=c("#66bd63","#b2182b"),labels = c("Retained", "Excluded")) +
+ geom_hline(yintercept = 0.1,linetype="dashed",size=.3) +
+ geom_vline(xintercept = 0.1,linetype="dashed",size=.3) +
+ geom_abline(intercept = 0.9, slope=-1,linetype="dashed",size=.3) +
+ labs(title="Exclusion of markers with mark_prop()",
+ x="Proportion of homozygous individuals AA",
+ y="Proportion of homozygous individuals BB",
+ color="Exclusion") +
+ theme_classic() +
+ theme(aspect.ratio=0.8,
+ legend.position=c(0.8,0.8),
+ legend.title = element_blank()) +
+ theme(plot.title = element_text(hjust = 0.4,face="bold",size=14))
+
+prop_plot
+```
```{r}
tab2_data3 <- tab2
diff --git a/article/data3/data3.rda b/article/data3/data3.rda
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new file mode 100644
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new file mode 100644
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new file mode 100644
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--- /dev/null
+++ b/article/figures/figS3.svg
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