p("SHAMAN is a SHiny application for Metagenomic ANalysis including the normalization,
the differential analysis and mutiple visualization.",style="font-family: 'times'; font-si16pt"),
p("SHAMAN is based on DESeq2 R package",a("[Anders and Huber 2010]",href="http://www.ncbi.nlm.nih.gov/pubmed/20979621"),"for the analysis of metagenomic data, as suggested in",a("[McMurdie and Holmes 2014,",href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974642/"),a("Jonsson2016]",href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727335/"),