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General help/documentation

Generalities that need to be provided somehow to the user.

  • provide a dummy infile

Write somewhere that:

  • input file must be tsv (or csv ? to decide)
  • phenotypic values must be written US/UK format: dots instead of comma
  • cc-qtl currently performs linear, not logistic regression: that means, only continuous, not binary traits can be taken into account
  • to satisfy the stats hypotheses underlying QTL mapping, phenotypic data must be pseudo-gaussian. It is advised that before feeding your data to ccqtl, you first plot them to see if the distribution grossly satisfies a gaussian. If it is not the case, several mathematicals transformations of your data can be considered...
  • what type of transformation given the data ? from R to L. Strongly right-skewed: log ; slitghly right-skewed : square-root ; left-skewed : power. See pig dingy for a generic reminder (ref = https://www.davidzeleny.net/anadat-r/doku.php/en:data_preparation)
Edited by Victoire BAILLET