PD-T4-8 is composed of a single protein that contains a DUF4263 domain found in the Shedu defence system :ref{doi=10.1038/s41564-022-01219-4}. PD-T4-8 from *Escherichia coli* RCP52534.1 confers resistance against T2, T4, T6, SECphi18 and SECphi27.
## Molecular mechanisms
As far as we are aware, the molecular mechanism is unknown.