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content/3.defense-systems/rst_helicaseduf2290.md
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## Description
The Rst_HelicaseDUF2290 system was discovered during a screen for defense systems targeted at hotspots of antiphage activity in phages and phage-satellites.
The Rst_HelicaseDUF2290 system was discovered during a screen for defense systems targeted at hotspots of antiphage activity in phages and phage-satellites. It is composed of 2 proteins, an helicase and a protein with the domain DUF2290.
## Molecular mechanism