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Commit 6df04a6d authored by Victoire  BAILLET's avatar Victoire BAILLET
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add CITATION.cff file (very first version)

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# This CITATION.cff file was generated with cffinit.
# Visit https://bit.ly/cffinit to generate yours today!
cff-version: 1.2.0
title: CCQTL
message: >-
If you use this software, please cite it using the
metadata from this file.
type: software
authors:
- given-names: Remi
family-names: Planel
email: remi.planel@pasteur.fr
affiliation: >-
Université Paris Cité, Bioinformatics and
Biostatistics Hub, F-75015 Paris, France
orcid: 'https://orcid.org/0000-0002-7826-3316'
- given-names: Victoire
family-names: Baillet
email: victoire.baillet@pasteur.fr
affiliation: >-
Institut Pasteur, Université Paris Cité,
Bioinformatics and Biostatistics Hub, F-75015 Paris,
France
orcid: 'https://orcid.org/0000-0002-1081-2921'
- given-names: Vincent
family-names: Guillemot
orcid: 'https://orcid.org/0000-0002-7421-0655'
email: vincent.guillemot@pasteur.fr
affiliation: >-
Institut Pasteur, Université Paris Cité,
Bioinformatics and Biostatistics Hub, F-75015 Paris,
France
- given-names: Pascal
family-names: Campagne
email: pascal.campagne@pasteur.fr
affiliation: >-
Institut Pasteur, Université Paris Cité,
Bioinformatics and Biostatistics Hub, F-75015 Paris,
France
orcid: 'https://orcid.org/0000-0001-7018-1896'
identifiers:
- type: swh
value: 'swh:1:dir:2acedd6f278157b5b0112245f0febc23a45937ef'
description: >-
Software Heritage identifier for version 1.0.0 of the
work.
repository-code: 'https://gitlab.pasteur.fr/cc-qtl/cc-qtl-db'
abstract: >-
Quantitative Trait Locus (QTL) mapping in mapping
populations and Genome-Wide Association Studies (GWAS) in
natural populations are complementary approaches for
dissecting the genetic architecture of complex traits.
While GWAS are typically carried out by statistical
genetics groups well-versed in quantitative environments
and code management, experimental geneticists performing
QTL mapping focus on labor-intensive phenotyping
experiments thus requiring further support, both for code
and statistics, to benefit from best practices in the
field.
We present CCQTL, a comprehensive platform for QTL mapping
in the Collaborative Cross (CC), an increasingly used
mouse mapping population. CCQTL features an intuitive
graphical user interface (GUI) for seamless end-to-end QTL
mapping analysis, from data transformation to candidate
gene identification. It also includes a robust database
structure ensuring secure, organized storage of phenotypic
data, accompanied by an advanced permissions system.
CCQTL's analytical component leverages R/qtl2 tools
integrated into preconfigured Galaxy workflows designed
explicitly for the CC. This setup facilitates one-click,
reproducible analyses. The platform's interface (GUI,
database, and analytics) is containerized using Docker,
enabling straightforward deployment and scalability. While
primarily designed to empower non-specialists in
conducting their own data analyses, CCQTL's Galaxy-brought
reproducibility and sophisticated database permission
system also renders it valuable for experienced users
seeking streamlined solutions.
keywords:
- QTL mapping
- Collaborative Cross
- Web interface
- Database
- Galaxy
license: GPL-3.0
version: 1.0.0
date-released: '2023-07-07'
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