Add todo

crisprbact/off_target.py

@@ -18,6 +18,7 @@ def get_off_target_pos(guide, recs, seed_size):
             # + ori
             offs_plus = re.finditer(guide[-seed_size:] + "[ATGC]GG", str(rec.seq))
             offs = [match.span() + (match.end(), "+", rec.id) for match in offs_plus]
+            # TODO: comparer guide avec rec.seq[match.start():match.end()]
             # - ori
             offs_minus = re.finditer(
                 "CC[ATGC]" + rev_comp(guide[-seed_size:]), str(rec.seq)
@@ -25,6 +26,8 @@ def get_off_target_pos(guide, recs, seed_size):
             offs += [
                 match.span() + (match.start(), "-", rec.id) for match in offs_minus
             ]
+            # comparer guide avec rec.seq[match.start():match.end()].reverse_complement()
+            # comparer les positions identique à partir de la fin et d'affilé.
             offs_dict = dict(
                 zip(["start", "end", "pampos", "strand", "recid"], zip(*offs))
             )