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Commit 137e4a9e authored by Jean  CURY's avatar Jean CURY
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Update nlr.md

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......@@ -11,6 +11,7 @@ tableColumns:
Effector: Unknown
PFAM: PF05729
contributors:
- Héloïse Georjon
relevantAbstract:
- doi: 10.1016/j.cell.2023.04.015
---
......@@ -20,7 +21,7 @@ relevantAbstract:
Several proteins containing a NACHT module were found to have anti-phage activity. NACHT modules are also found in metazoans, where they play a role in innate immunity.
bNacht systems have some similarities with other defense systems:
[CARD_NLR](https://defense-finder.pasteur.cloud/wiki/defense-systems/card_nlr) , [Rst_TIR-NLR](https://defense-finder.pasteur.cloud/wiki/defense-systems/rst_tir-nlr), [Avs](https://defense-finder.pasteur.cloud/wiki/defense-systems/avs).
[CARD_NLR](/defense-systems/card_nlr) , [Rst_TIR-NLR](/defense-systems/rst_tir-nlr), [Avs](/defense-systems/avs).
## Molecular mechanism
Bacterial NACHT module-containing proteins (bNACHT) encompass a C-terminal sensor, a central NACHT module, and N-terminal effector modules. The N-terminal effectors associated with bNACHT proteins are diverse, and include domains that have been previously described to be involved in other defense systems {doi=10.1016/j.cell.2023.04.015}
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