Merge branch 'lpaoli-main-patch-78102' into 'main'

Update kiwa.md according to Hackaton guidelines, see...

See merge request !46

content/3.defense-systems/kiwa.md

@@ -10,9 +10,22 @@ tableColumns:
     Activator: Unknown
     Effector: Unknown
     PFAM: PF16162
+contributors: 
+  - Lucas Paoli
+relevantAbstracts:
+  - doi: 10.1126/science.aar4120
+  - doi: 10.1101/2023.02.26.530102
 ---
 
 # Kiwa
+
+## Description
+
+The Kiwa antiviral defense system was first described in :ref{doi=10.1126/science.aar4120} and further described in :ref{doi=10.1101/2023.02.26.530102}. It is named after one of the divine guardians of the ocean in the Māori traditions. Kiwa is composed of two proteins: KwaA and KwaB. 
+## Molecular mechanisms
+
+KwaA detects phage infection by detecting the inhibition of the host RNA polymerase by phages. This triggers the reponse by KwaB, which decreases phage DNA replication through a RecBCD-depdendent pathway :ref{doi=10.1101/2023.02.26.530102}.
+
 ## Example of genomic structure
 
 The Kiwa system is composed of 2 proteins: KwaA and, KwaB.
@@ -76,13 +89,4 @@ end
     style Title3 fill:none,stroke:none,stroke-width:none
     style Title4 fill:none,stroke:none,stroke-width:none
 </mermaid>
-## Relevant abstracts
-
-::relevant-abstracts
----
-items:
-    - doi: 10.1126/science.aar4120
-
----
-::