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...@@ -10,11 +10,29 @@ tableColumns: ...@@ -10,11 +10,29 @@ tableColumns:
Activator: Unknown Activator: Unknown
Effector: Unknown Effector: Unknown
PFAM: PF14350 PFAM: PF14350
contributors:
- Florian Tesson
relevantAbstracts: relevantAbstracts:
- doi: 10.1016/j.chom.2022.02.018 - doi: 10.1016/j.chom.2022.02.018
--- ---
# Rst_gop_beta_cll # Rst_gop_beta_cll
## Description
The gop-beta-cll system was shown to have an antiphage activity in 2022 :ref{doi=10.1016/j.chom.2022.02.018} against Escherichia coli phage lambda and P1.
The gop-beta-cll was first described as a nonessential region of the bacteriophage P4 :ref{doi=10.1128/jvi.64.1.24-36.1990}.
This system is composed of 3 genes: gop, beta and cll.
## Molecular mechanism
As far as we are aware, the molecular mechanism is unknown.
The production of the gop protein without beta is toxic :ref{doi=10.1128/jvi.64.1.24-36.1990} suggesting a toxin antitoxin mechanism :ref{doi=10.1016/j.chom.2022.02.018}.
## Example of genomic structure ## Example of genomic structure
The Rst_gop_beta_cll is composed of 3 proteins: beta, cll and gop. The Rst_gop_beta_cll is composed of 3 proteins: beta, cll and gop.
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