Update olokun.md

content/3.defense-systems/olokun.md

@@ -4,14 +4,32 @@ layout: article
 tableColumns:
     article:
       doi: 10.1016/j.chom.2022.09.017
-      abstract: |
+      abstract: 
         Bacterial anti-phage systems are frequently clustered in microbial genomes, forming defense islands. This property enabled the recent discovery of multiple defense systems based on their genomic co-localization with known systems, but the full arsenal of anti-phage mechanisms remains unknown. We report the discovery of 21 defense systems that protect bacteria from phages, based on computational genomic analyses and phage-infection experiments. We identified multiple systems with domains involved in eukaryotic antiviral immunity, including those homologous to the ubiquitin-like ISG15 protein, dynamin-like domains, and SEFIR domains, and show their participation in bacterial defenses. Additional systems include domains predicted to manipulate DNA and RNA molecules, alongside toxin-antitoxin systems shown here to function in anti-phage defense. These systems are widely distributed in microbial genomes, and in some bacteria, they form a considerable fraction of the immune arsenal. Our data substantially expand the inventory of defense systems utilized by bacteria to counteract phage infection.
     Sensor: Unknown
     Activator: Unknown
     Effector: Unknown
+    PFAM: PF01602, PF18742
+
+contributors: 
+  - Helena Shomar, Marie Guillaume
+relevantAbstracts:
+  - doi: doi: 10.1016/j.chom.2022.09.017
+
 ---
 
 # Olokun
+
+## Description
+
+The system Olokun  is composed of 2 genes OloA (Adaptin_N domain) and OloB (nuclease domain) of unknown function.
+This system was experimentally validated in _Escherichia coli_ and protects against LambdaVir and SECphi27 infection.
+
+The system is named after a revered deity of the Yoruba religion, associated with the deep sea and depicted as an enormously powerful figure. They are believed to posses immense wealth, are associated with health, fertility and prosperity, and revered for their ability for inducing profound transformation and renewal. They are frequently depicted as a mermaid or merman, with both masculine and feminine aspects, reflecting the diversity and depth of the ocean.
+
+## Molecular mechanisms
+To our knowledde, the molecular mechanism is unknown. Please update.
+
 ## Example of genomic structure
 
 The Olokun system is composed of 2 proteins: OloA and, OloB.
@@ -75,12 +93,3 @@ end
     style Title3 fill:none,stroke:none,stroke-width:none
     style Title4 fill:none,stroke:none,stroke-width:none
 </mermaid>
-## Relevant abstracts
-
-::relevant-abstracts
----
-items:
-    - doi: 10.1016/j.chom.2022.09.017
-
----
-::