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Commit 7cdfcfed authored by Remi  PLANEL's avatar Remi PLANEL
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...@@ -9,7 +9,7 @@ Bacteriophages, or phages for short, are viruses that infect bacteria and hijack ...@@ -9,7 +9,7 @@ Bacteriophages, or phages for short, are viruses that infect bacteria and hijack
In response to this evolutionary pressure, bacteria have developed an arsenal of anti-phage defense systems. The term "defense system" here designates either a single gene or a set of genes, which expression provides the bacteria with some level of resistance against phage infection. In response to this evolutionary pressure, bacteria have developed an arsenal of anti-phage defense systems. The term "defense system" here designates either a single gene or a set of genes, which expression provides the bacteria with some level of resistance against phage infection.
# History ## History
The first anti-phage defense system was discovered in the early 1950s by two separate teams of researchers (Luria and Human, 1952 ; Bertani and Wiegle 1952). Luria and Human reported a mysterious phenomenon, where one phage was only capable of infecting a specific bacterial strain once. The progeny phages produced by this first round of infection had lost their ability to infect the same strain again, yet remained able to infect other bacterial strains. For them, this could only mean that "the genotype of the host in which a virus reproduces affects the phenotype of the new virus" (Luria and Human, 1952). A similar phenomenon was shortly after described by Bertani and Wiegle. The first anti-phage defense system was discovered in the early 1950s by two separate teams of researchers (Luria and Human, 1952 ; Bertani and Wiegle 1952). Luria and Human reported a mysterious phenomenon, where one phage was only capable of infecting a specific bacterial strain once. The progeny phages produced by this first round of infection had lost their ability to infect the same strain again, yet remained able to infect other bacterial strains. For them, this could only mean that "the genotype of the host in which a virus reproduces affects the phenotype of the new virus" (Luria and Human, 1952). A similar phenomenon was shortly after described by Bertani and Wiegle.
...@@ -83,5 +83,3 @@ LURIA SE, HUMAN ML. A nonhereditary, host-induced variation of bacterial viruses ...@@ -83,5 +83,3 @@ LURIA SE, HUMAN ML. A nonhereditary, host-induced variation of bacterial viruses
Makarova KS, Wolf YI, Snir S, Koonin EV. Defense islands in bacterial and archaeal genomes and prediction of novel defense systems. J Bacteriol. 2011 Nov;193(21):6039-56. doi: 10.1128/JB.05535-11. Epub 2011 Sep 9. PMID: 21908672; PMCID: PMC3194920. Makarova KS, Wolf YI, Snir S, Koonin EV. Defense islands in bacterial and archaeal genomes and prediction of novel defense systems. J Bacteriol. 2011 Nov;193(21):6039-56. doi: 10.1128/JB.05535-11. Epub 2011 Sep 9. PMID: 21908672; PMCID: PMC3194920.
Tal N, Sorek R. SnapShot: Bacterial immunity. Cell. 2022 Feb 3;185(3):578-578.e1. doi: 10.1016/j.cell.2021.12.029. PMID: 35120666. Tal N, Sorek R. SnapShot: Bacterial immunity. Cell. 2022 Feb 3;185(3):578-578.e1. doi: 10.1016/j.cell.2021.12.029. PMID: 35120666.
...@@ -34,7 +34,6 @@ Paris type I system in _Salmonella enterica_ (GCF\__000006945.2). AriA_I:_ NP_46 ...@@ -34,7 +34,6 @@ Paris type I system in _Salmonella enterica_ (GCF\__000006945.2). AriA_I:_ NP_46
<br/> <br/>
Paris type I merge system in _Sideroxydans lithotrophicus_ (GCF\__000025705.1). AriAB_I:_ WP_013030315.1 Paris type I merge system in _Sideroxydans lithotrophicus_ (GCF\__000025705.1). AriAB_I:_ WP_013030315.1
### Paris type II ### Paris type II
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# AVAST ---
title: AVAST
---
# AVAST System
AVAST (antiviral ATPases/NTPases of the STAND superfamily) is a group of anti-phage defense systems, active against some dsDNA phages. AVAST (antiviral ATPases/NTPases of the STAND superfamily) is a group of anti-phage defense systems, active against some dsDNA phages.
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...@@ -2,7 +2,9 @@ ...@@ -2,7 +2,9 @@
export default defineNuxtConfig({ export default defineNuxtConfig({
modules: ['@nuxt/content', '@invictus.codes/nuxt-vuetify'], modules: ['@nuxt/content', '@invictus.codes/nuxt-vuetify'],
content: { content: {
documentDriven: true documentDriven: {
injectPage: false
}
}, },
vuetify: { vuetify: {
vuetifyOptions: { vuetifyOptions: {
......
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