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Commit 875762c0 authored by Jean  CURY's avatar Jean CURY
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Update rst_2tm_1tm_tir.md

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## Description ## Description
The Rst_2TM_1TM_TIR system is carried by the P2-like phage AC1 and protects *Escherichia coli* C against lambda, LF82_P8 and P2 phages. This system is composed of three proteins, Rst_TIR_tm, that contains a TIR ( Toll/interleukin-1 receptor) domain, Rst_1TM_TIR, that contains a transmembrane helix (TM) and Rst_2TM_TIR, that contains two TMs :ref{doi=10.1016/j.chom.2022.02.018}. Rousset et al. suggested that the TIR containing protein could generate a nucleotide messenger that in turn could activate the associated transmembrane proteins. The Rst_2TM_1TM_TIR system is carried by the P2-like phage AC1 and protects *Escherichia coli* C against lambda, LF82_P8 and P2 phages. This system is composed of three proteins, Rst_TIR_tm, that contains a TIR (Toll/interleukin-1 receptor) domain, Rst_1TM_TIR, that contains a transmembrane helix (TM) and Rst_2TM_TIR, that contains two TMs :ref{doi=10.1016/j.chom.2022.02.018}. Rousset et al. suggested that the TIR containing protein could generate a nucleotide messenger that in turn could activate the associated transmembrane proteins.
## Molecular mechanisms ## Molecular mechanisms
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