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......@@ -10,13 +10,32 @@ tableColumns:
Activator: Unknown
Effector: Unknown
PFAM: PF00078
contributors:
- Florian Tesson
relevantAbstracts:
- doi: 10.1023/A:1002027321171
- doi: 10.1016/j.mib.2005.06.006
- doi: 10.1093/nar/gkac467
- doi: 10.1023/A:1002027321171
- doi: 10.1016/j.mib.2005.06.006
- doi: 10.1093/nar/gkac467
- doi: 10.1128/aem.63.4.1274-1283.1997
---
# AbiK
## Description
The AbiK defense system was discovered in 1997 in *Lactococcus lactis* :ref{doi=10.1128/aem.63.4.1274-1283.1997}. AbiK is a single gene system with a size of around 650 amino acids.
AbiK is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry :ref{doi=10.1016/j.mib.2005.06.006}. AbiK is classified as abortive infection in :ref{doi=10.1016/j.mib.2023.102312}.
Since it was discovered a similarity in amino acids was found with [AbiA](/defense-systems/abia).
However, with the discovery of dozens of new systems, it was categorized as one of the UG/Abi defense systems :ref{doi=10.1093/nar/gkac467} along with [DRT](/defense-systems/drt) different subsystems, [AbiA](/defense-systems/abia), [AbiP2](/defense-systems/abip2) and [Rst_RT_Nitralase_TM](/defense-systems/rst_rt-nitrilase-tm).
Those systems are characterized by the presence of a reverse transcriptase domain of the "Unknown Group RT".
## Molecular mechanism
To our knowledge, the molecular mechanism is unknown. Similarly, for the other systems of this family, the molecular mechanism remains unknown.
## Example of genomic structure
The AbiK is composed of 1 protein: AbiK.
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