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Commit 90561bdb authored by Jean  CURY's avatar Jean CURY
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Update pd-t4-4.md

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......@@ -10,9 +10,19 @@ tableColumns:
Activator: Unknown
Effector: Unknown
PFAM: PF13175, PF13304
contributors:
- Nathalie Bechon
relevantAbstracts
- doi: 10.1038/s41564-022-01219-4
---
# PD-T4-4
## Description
PD-T4-4 is a defense system composed of two proteins, a P-loop NTPase and a nuclease, that is most likely protecting the bacterial population through abortive infection. It was identified from an ICE in an *E. coli* genome.
## Molecular mechanisms
PD-T4-4 molecular mechanism is currently unknown, although it is most likely an abortive infection system.
## Example of genomic structure
The PD-T4-4 system is composed of 2 proteins: PD-T4-4_A and, PD-T4-4_B.
......@@ -21,7 +31,7 @@ Here is an example found in the RefSeq database:
![pd-t4-4](/pd-t4-4/PD-T4-4.svg){max-width=750px}
PD-T4-4 system in the genome of *Escherichia coli* (GCF_013376895.1) is composed of 2 proteins: PD-T4-4_B (WP_176670803.1)and, PD-T4-4_A (WP_027920142.1).
PD-T4-4 system in the genome of *Escherichia coli* (GCF_013376895.1) is composed of 2 proteins: PD-T4-4_B (WP_176670803.1) and, PD-T4-4_A (WP_027920142.1).
## Distribution of the system among prokaryotes
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style Title4 fill:none,stroke:none,stroke-width:none
</mermaid>
## Relevant abstracts
::relevant-abstracts
---
items:
- doi: 10.1038/s41564-022-01219-4
---
::
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